| Literature DB >> 31913641 |
Tianbao Yang1, Huiai Lu2, Yixuan Shu2, Yifeng Ou1, Ling Hong2, Chak-Tong Au3, Renhua Qiu1.
Abstract
A concise, one-step route to produce 3,3'-diindolylmethanes (DIMs) from simple indoles and ketones or aldehydes is reported. The key step is the ready formation of indole derivatives that involves the in situ conversion of CF3SO2Na reagent to ·CF3 under oxygen or air (1.0 atm) and UV irradiation. It is disclosed that most of the obtained DIMs show anticancer activities in human bladder cancer cell lines EJ and T24.Entities:
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Year: 2020 PMID： 31913641 DOI： 10.1021/acs.orglett.9b04272
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005