Literature DB >> 31911671

Reactivation of γ-globin expression through Cas9 or base editor to treat β-hemoglobinopathies.

Liren Wang1, Linxi Li1, Yanlin Ma2,3, Handan Hu1, Qi Li2,3, Yang Yang4, Wenbang Liu1, Shuming Yin1, Wei Li5, Bin Fu6, Ryo Kurita7, Yukio Nakamura8, Mingyao Liu9, Yongrong Lai10, Dali Li11.   

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Year:  2020        PMID： 31911671      PMCID： PMC7054297          DOI： 10.1038/s41422-019-0267-z

Source DB:  PubMed          Journal:  Cell Res        ISSN： 1001-0602            Impact factor:   25.617


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  19 in total

Review 1.  Manipulation of Developmental Gamma-Globin Gene Expression: an Approach for Healing Hemoglobinopathies.

Authors:  Vigneshwaran Venkatesan; Saranya Srinivasan; Prathibha Babu; Saravanabhavan Thangavel
Journal:  Mol Cell Biol       Date:  2020-12-21       Impact factor: 4.272

2.  Genome editing strategies for fetal hemoglobin induction in beta-hemoglobinopathies.

Authors:  Selami Demirci; Alexis Leonard; John F Tisdale
Journal:  Hum Mol Genet       Date:  2020-09-30       Impact factor: 6.150

3.  Epigenetic inactivation of ERF reactivates γ-globin expression in β-thalassemia.

Authors:  Xiuqin Bao; Xinhua Zhang; Liren Wang; Zhongju Wang; Jin Huang; Qianqian Zhang; Yuhua Ye; Yongqiong Liu; Diyu Chen; Yangjin Zuo; Qifa Liu; Peng Xu; Binbin Huang; Jianpei Fang; Jinquan Lao; Xiaoqin Feng; Yafeng Li; Ryo Kurita; Yukio Nakamura; Weiwei Yu; Cunxiang Ju; Chunbo Huang; Narla Mohandas; Dali Li; Cunyou Zhao; Xiangmin Xu
Journal:  Am J Hum Genet       Date:  2021-03-17       Impact factor: 11.025

Review 4.  Exploring the crosstalk between long non-coding RNAs and microRNAs to unravel potential prognostic and therapeutic biomarkers in β-thalassemia.

Authors:  Motiur Rahaman; Mandrita Mukherjee; Shatarupa Bhattacharya; Budhaditya Mukherjee; Praphulla Chandra Shukla; Tuphan Kanti Dolai; Nishant Chakravorty
Journal:  Mol Biol Rep       Date:  2022-06-18       Impact factor: 2.742

Review 5.  New therapeutics for primary hyperoxaluria type 1.

Authors:  Pegah Dejban; John C Lieske
Journal:  Curr Opin Nephrol Hypertens       Date:  2022-03-09       Impact factor: 3.416

6.  In vivo HSPC gene therapy with base editors allows for efficient reactivation of fetal γ-globin in β-YAC mice.

Authors:  Chang Li; Aphrodite Georgakopoulou; Arpit Mishra; Sucheol Gil; R David Hawkins; Evangelia Yannaki; André Lieber
Journal:  Blood Adv       Date:  2021-02-23

7.  Increasing the efficiency and targeting range of cytidine base editors through fusion of a single-stranded DNA-binding protein domain.

Authors:  Xiaohui Zhang; Liang Chen; Biyun Zhu; Liren Wang; Caiyu Chen; Mengjia Hong; Yifan Huang; Huiying Li; Honghui Han; Bailian Cai; Weishi Yu; Shuming Yin; Lei Yang; Zuozhen Yang; Meizhen Liu; Ying Zhang; Zhiyong Mao; Yuxuan Wu; Mingyao Liu; Dali Li
Journal:  Nat Cell Biol       Date:  2020-05-11       Impact factor: 28.824

8.  Amelioration of an Inherited Metabolic Liver Disease through Creation of a De Novo Start Codon by Cytidine Base Editing.

Authors:  Lei Yang; Liren Wang; Yanan Huo; Xi Chen; Shuming Yin; Yaqiang Hu; Xiaohui Zhang; Rui Zheng; Hongquan Geng; Honghui Han; Xueyun Ma; Meizhen Liu; Haibo Li; Weishi Yu; Mingyao Liu; Jun Wang; Dali Li
Journal:  Mol Ther       Date:  2020-05-07       Impact factor: 11.454

Review 9.  Novel genome-editing-based approaches to treat motor neuron diseases: Promises and challenges.

Authors:  Annarita Miccio; Panagiotis Antoniou; Sorana Ciura; Edor Kabashi
Journal:  Mol Ther       Date:  2021-04-03       Impact factor: 11.454

Review 10.  CRISPR/Cas9 gene editing for curing sickle cell disease.

Authors:  So Hyun Park; Gang Bao
Journal:  Transfus Apher Sci       Date:  2021-01-10       Impact factor: 1.764
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