Mark H Ereth1, Donald H Hess2, Abigail Driscoll3, Mark Hernandez4, Frank Stamatatos2. 1. Department of Anesthesiology, Mayo Clinic College of Medicine and Science, Rochester, MN. Electronic address: ereth.mark@mayo.edu. 2. SecureAire, LLC, Dunedin, FL. 3. University of Minnesota School of Medicine, Minneapolis, MN. 4. Department of Environmental Engineering, University of Colorado Boulder, Boulder, CO.
Abstract
BACKGROUND: Controlling indoor air quality and the airborne transmission of infectious agents in hospitals is critical. The most hazardous particles and pathogens are not easily eliminated by traditionally passive air cleansing. METHODS: We studied the effect of a novel particle control technology on airborne particulate matter in 2 live real-world operating room settings and on pathogen survival in a microbiology laboratory. RESULTS: Particle control technology reduced operating room particle and pathogen loads by 94.4% in a community hospital operating room, and by 95% in an academic medical center operating room. The addition of particle control technology to a collector loaded with a biologic warfare surrogate resulted in a 95% kill rate of an anthrax surrogate (Bacillus subtilis) within 3 hours. DISCUSSION: Deployment of this emerging technology could significantly reduce indoor air contamination and associated infections in operating rooms, hospital isolation rooms, and intensive care settings, as well as reduce inflammatory responses to airborne particles. CONCLUSIONS: The particle control technology studied may protect patients from hospital-acquired infections, reduce inflammatory pulmonary disease, and mitigate exposure to biologic weapons.
BACKGROUND: Controlling indoor air quality and the airborne transmission of infectious agents in hospitals is critical. The most hazardous particles and pathogens are not easily eliminated by traditionally passive air cleansing. METHODS: We studied the effect of a novel particle control technology on airborne particulate matter in 2 live real-world operating room settings and on pathogen survival in a microbiology laboratory. RESULTS: Particle control technology reduced operating room particle and pathogen loads by 94.4% in a community hospital operating room, and by 95% in an academic medical center operating room. The addition of particle control technology to a collector loaded with a biologic warfare surrogate resulted in a 95% kill rate of an anthrax surrogate (Bacillus subtilis) within 3 hours. DISCUSSION: Deployment of this emerging technology could significantly reduce indoor air contamination and associated infections in operating rooms, hospital isolation rooms, and intensive care settings, as well as reduce inflammatory responses to airborne particles. CONCLUSIONS: The particle control technology studied may protect patients from hospital-acquired infections, reduce inflammatory pulmonary disease, and mitigate exposure to biologic weapons.
Authors: Vicky Yamamoto; Joe F Bolanos; John Fiallos; Susanne E Strand; Kevin Morris; Sanam Shahrokhinia; Tim R Cushing; Lawrence Hopp; Ambooj Tiwari; Robert Hariri; Rick Sokolov; Christopher Wheeler; Ajeet Kaushik; Ashraf Elsayegh; Dawn Eliashiv; Rebecca Hedrick; Behrouz Jafari; J Patrick Johnson; Mehran Khorsandi; Nestor Gonzalez; Guita Balakhani; Shouri Lahiri; Kazem Ghavidel; Marco Amaya; Harry Kloor; Namath Hussain; Edmund Huang; Jason Cormier; J Wesson Ashford; Jeffrey C Wang; Shadi Yaghobian; Payman Khorrami; Bahman Shamloo; Charles Moon; Payam Shadi; Babak Kateb Journal: J Alzheimers Dis Date: 2020 Impact factor: 4.472