| Literature DB >> 31909398 |
Kouki Shinoda1, Akiyo Suda1, Kenko Otonari1, Shiroh Futaki1, Miki Imanishi1.
Abstract
New methods to control local RNA methylation are needed to elucidate the function of individual m6A. Here, fusion proteins between the programmable RNA binding protein PUF and the m6A demethylase FTO or METTL14 methyltransferase were designed. FTO-PUFs and METTL14-PUFs showed sequence-specific RNA demethylation and methylation activities, respectively.Entities:
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Year: 2020 PMID： 31909398 DOI： 10.1039/c9cc09298f
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222