Literature DB >> 31907876

Availability of Medications for the Treatment of Alcohol and Opioid Use Disorder in the USA.

Amanda J Abraham1, Christina M Andrews2, Samantha J Harris3, Peter D Friedmann4.   

Abstract

Despite high mortality rates due to opioid overdose and excessive alcohol consumption, medications for the treatment of alcohol and opioid use disorder have not been widely used in the USA. This paper provides an overview of the literature on the availability of alcohol and opioid used disorder medications in the specialty substance use disorder treatment system, other treatment settings and systems, and among providers with a federal waiver to prescribe buprenorphine. We also present the most current data on the availability of alcohol and opioid use disorder medications in the USA. These estimates show steady growth in availability of opioid use disorder medications over the past decade and a decline in availability of alcohol use disorder medications. However, overall use of medications in the USA remains low. In 2017, only 16.3% of specialty treatment programs offered any single medication for alcohol use disorder treatment and 35.5% offered any single medication for opioid use disorder treatment. Availability of buprenorphine-waivered providers has increased significantly since 2002. However, geographic disparities in access to buprenorphine remain. Some of the most promising strategies to increase availability of alcohol and opioid use disorder medications include the following: incorporating substance use disorder training in healthcare education programs, educating the substance use disorder workforce about the benefits of medication treatment, reducing stigma surrounding the use of medications, implementing medications in primary care settings, implementing integrated care models, revising regulations on methadone and buprenorphine, improving health insurance coverage of medications, and developing novel medications for the treatment of substance use disorder.

Entities:  

Keywords:  Alcohol use disorder; buprenorphine-waivered providers.; medication treatment; opioid use disorder; specialty treatment

Mesh:

Year:  2020        PMID: 31907876      PMCID: PMC7007488          DOI: 10.1007/s13311-019-00814-4

Source DB:  PubMed          Journal:  Neurotherapeutics        ISSN: 1878-7479            Impact factor:   7.620


  109 in total

1.  Counseling plus buprenorphine-naloxone maintenance therapy for opioid dependence.

Authors:  David A Fiellin; Michael V Pantalon; Marek C Chawarski; Brent A Moore; Lynn E Sullivan; Patrick G O'Connor; Richard S Schottenfeld
Journal:  N Engl J Med       Date:  2006-07-27       Impact factor: 91.245

2.  Predictors of outcome for short-term medically supervised opioid withdrawal during a randomized, multicenter trial of buprenorphine-naloxone and clonidine in the NIDA clinical trials network drug and alcohol dependence.

Authors:  Douglas M Ziedonis; Leslie Amass; Marc Steinberg; George Woody; Jonathan Krejci; Jeffrey J Annon; Allan J Cohen; Nancy Waite-O'Brien; Susan M Stine; Dennis McCarty; Malcolm S Reid; Lawrence S Brown; Robert Maslansky; Theresa Winhusen; Dean Babcock; Greg Brigham; Joan Muir; Deborah Orr; Betty J Buchan; Terry Horton; Walter Ling
Journal:  Drug Alcohol Depend       Date:  2008-09-20       Impact factor: 4.492

3.  Injectable extended-release naltrexone for opioid dependence.

Authors:  Evgeny Krupitsky; Edward V Nunes; Walter Ling; Ari Illeperuma; David R Gastfriend; Bernard L Silverman
Journal:  Lancet       Date:  2011-08-20       Impact factor: 79.321

4.  The Economic Burden of Prescription Opioid Overdose, Abuse, and Dependence in the United States, 2013.

Authors:  Curtis S Florence; Chao Zhou; Feijun Luo; Likang Xu
Journal:  Med Care       Date:  2016-10       Impact factor: 2.983

5.  Bringing buprenorphine-naloxone detoxification to community treatment providers: the NIDA Clinical Trials Network field experience.

Authors:  Leslie Amass; Walter Ling; Thomas E Freese; Chris Reiber; Jeffrey J Annon; Allan J Cohen; Dennis McCarty; Malcolm S Reid; Lawrence S Brown; Cynthia Clark; Douglas M Ziedonis; Jonathan Krejci; Susan Stine; Theresa Winhusen; Greg Brigham; Dean Babcock; Joan A Muir; Betty J Buchan; Terry Horton
Journal:  Am J Addict       Date:  2004

Review 6.  Efficacy and safety of naltrexone and acamprosate in the treatment of alcohol dependence: a systematic review.

Authors:  Carmen Bouza; Magro Angeles; Angeles Magro; Ana Muñoz; José María Amate
Journal:  Addiction       Date:  2004-07       Impact factor: 6.526

Review 7.  Efficacy of maintenance treatment with naltrexone for opioid dependence: a meta-analytical review.

Authors:  Björn Axel Johansson; Mats Berglund; Anna Lindgren
Journal:  Addiction       Date:  2006-04       Impact factor: 6.526

8.  Injectable, sustained-release naltrexone for the treatment of opioid dependence: a randomized, placebo-controlled trial.

Authors:  Sandra D Comer; Maria A Sullivan; Elmer Yu; Jami L Rothenberg; Herbert D Kleber; Kyle Kampman; Charles Dackis; Charles P O'Brien
Journal:  Arch Gen Psychiatry       Date:  2006-02

9.  Naltrexone and coping skills therapy for alcohol dependence. A controlled study.

Authors:  S S O'Malley; A J Jaffe; G Chang; R S Schottenfeld; R E Meyer; B Rounsaville
Journal:  Arch Gen Psychiatry       Date:  1992-11

10.  Contribution of excessive alcohol consumption to deaths and years of potential life lost in the United States.

Authors:  Mandy Stahre; Jim Roeber; Dafna Kanny; Robert D Brewer; Xingyou Zhang
Journal:  Prev Chronic Dis       Date:  2014-06-26       Impact factor: 2.830

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  12 in total

1.  Primary care experiences of veterans with opioid use disorder in the Veterans Health Administration.

Authors:  Audrey L Jones; Stefan G Kertesz; Leslie R M Hausmann; Maria K Mor; Ying Suo; Warren B P Pettey; James H Schaefer; Adi V Gundlapalli; Adam J Gordon
Journal:  J Subst Abuse Treat       Date:  2020-02-29

2.  A systematic review of patients' and providers' perspectives of medications for treatment of opioid use disorder.

Authors:  Katharine Cioe; Breanne E Biondi; Rebecca Easly; Amanda Simard; Xiao Zheng; Sandra A Springer
Journal:  J Subst Abuse Treat       Date:  2020-09-22

3.  Role of Peer Coaches in Digital Interventions for MOUD Initiation and Maintenance.

Authors:  Renee Garett; Sean D Young
Journal:  Community Ment Health J       Date:  2022-08-01

4.  Assessing Naltrexone Prescribing and Barriers to Initiation for Alcohol Use Disorder: A Multidisciplinary, Multisite Survey.

Authors:  Jonathan G Leung; Prasanna P Narayanan; Matej Markota; Nathaniel E Miller; Kemuel L Philbrick; M Caroline Burton; Robert W Kirchoff
Journal:  Front Psychiatry       Date:  2022-05-10       Impact factor: 5.435

5.  A qualitative investigation of addiction counselors' perceptions and experiences implementing an open-access model for treating opioid use disorder.

Authors:  Lindsay M S Oberleitner; Lynn M Madden; Dharushana Muthulingam; Ruthanne Marcus; David E Oberleitner; Mark Beitel; Marina Gaeta; Joseph F Tamberelli; Declan T Barry
Journal:  J Subst Abuse Treat       Date:  2020-11-02

6.  Increased utilization of buprenorphine and methadone in 2018 compared to 2015 among Seattle-area persons who inject drugs.

Authors:  Elisabeth Poorman; Sara N Glick; Jonathan K D Hiser; Elenore Bhatraju; Judith I Tsui
Journal:  J Subst Abuse Treat       Date:  2021-03-19

7.  Adapting and scaling a single site DEA X-waiver training program to a statewide initiative: Implementing GetWaiveredTX.

Authors:  Jennifer S Potter; Erin P Finley; Van L King; Holly J Lanham; Susanne Schmidt; Suyen Schneegans; Kristen D Rosen
Journal:  J Subst Abuse Treat       Date:  2021-12-13

8.  Use of Medication for Opioid Use Disorder Among US Adolescents and Adults With Need for Opioid Treatment, 2019.

Authors:  Pia M Mauro; Sarah Gutkind; Erin M Annunziato; Hillary Samples
Journal:  JAMA Netw Open       Date:  2022-03-01

9.  Barriers and Motivators to Opioid Treatment Among Suburban Women Who Are Pregnant and Mothers in Caregiver Roles.

Authors:  Miriam Boeri; Aukje K Lamonica; Jeffrey M Turner; Amanda Parker; Grace Murphy; Carly Boccone
Journal:  Front Psychol       Date:  2021-07-01

10.  Gender disparities in access and retention in outpatient methadone treatment for opioid use disorder in low-income urban communities.

Authors:  Jeanne C Marsh; Hortensia Amaro; Yinfei Kong; Tenie Khachikian; Erick Guerrero
Journal:  J Subst Abuse Treat       Date:  2021-04-20
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