Literature DB >> 31903447

Bedtoolsr: An R package for genomic data analysis and manipulation.

Mayura N Patwardhan1, Craig D Wenger2, Eric S Davis3, Douglas H Phanstiel1,3,4,5.   

Abstract

The sequencing of the human genome and subsequent advances in DNA sequencing technology have created a need for computational tools to analyze and manipulate genomic data sets. The bedtools software suite and the R programming language have emerged as indispensable tools for this purpose but have lacked integration. Here we describe bedtoolsr, an R package that provides simple and intuitive access to all bedtools functions from within the R programming environment. We provide several usability enhancements, support compatibility with past and future versions of bedtools, and include unit tests to ensure stability. bedtoolsr provides a user-focused, harmonious integration of the bedtools software suite with the R programming language that should be of great use to the genomics community.

Entities:  

Year:  2019        PMID: 31903447      PMCID: PMC6941791          DOI: 10.21105/joss.01742

Source DB:  PubMed          Journal:  J Open Source Softw        ISSN: 2475-9066


  5 in total

1.  Programming tools: Adventures with R.

Authors:  Sylvia Tippmann
Journal:  Nature       Date:  2015-01-01       Impact factor: 49.962

2.  BEDTools: a flexible suite of utilities for comparing genomic features.

Authors:  Aaron R Quinlan; Ira M Hall
Journal:  Bioinformatics       Date:  2010-01-28       Impact factor: 6.937

3.  Software for computing and annotating genomic ranges.

Authors:  Michael Lawrence; Wolfgang Huber; Hervé Pagès; Patrick Aboyoun; Marc Carlson; Robert Gentleman; Martin T Morgan; Vincent J Carey
Journal:  PLoS Comput Biol       Date:  2013-08-08       Impact factor: 4.475

4.  Pybedtools: a flexible Python library for manipulating genomic datasets and annotations.

Authors:  Ryan K Dale; Brent S Pedersen; Aaron R Quinlan
Journal:  Bioinformatics       Date:  2011-09-23       Impact factor: 6.937

5.  valr: Reproducible genome interval analysis in R.

Authors:  Kent A Riemondy; Ryan M Sheridan; Austin Gillen; Yinni Yu; Christopher G Bennett; Jay R Hesselberth
Journal:  F1000Res       Date:  2017-06-29
  5 in total
  6 in total

1.  Plotgardener: Cultivating precise multi-panel figures in R.

Authors:  Nicole E Kramer; Eric S Davis; Craig D Wenger; Erika M Deoudes; Sarah M Parker; Michael I Love; Douglas H Phanstiel
Journal:  Bioinformatics       Date:  2022-02-04       Impact factor: 6.931

2.  Developing a 5-gene prognostic signature for cervical cancer by integrating mRNA and copy number variations.

Authors:  Wenxin Liu; Qiuying Jiang; Chao Sun; ShiHao Liu; Zhikun Zhao; Dongfang Wu
Journal:  BMC Cancer       Date:  2022-02-21       Impact factor: 4.430

3.  FusionAI, a DNA-sequence-based deep learning protocol reduces the false positives of human fusion gene prediction.

Authors:  Pora Kim; Hua Tan; Jiajia Liu; Himansu Kumar; Xiaobo Zhou
Journal:  STAR Protoc       Date:  2022-02-28

4.  Genomics-Based Reconstruction and Predictive Profiling of Amino Acid Biosynthesis in the Human Gut Microbiome.

Authors:  German A Ashniev; Sergey N Petrov; Stanislav N Iablokov; Dmitry A Rodionov
Journal:  Microorganisms       Date:  2022-03-30

5.  Genomic reconstruction of short-chain fatty acid production by the human gut microbiota.

Authors:  Maria S Frolova; Inna A Suvorova; Stanislav N Iablokov; Sergei N Petrov; Dmitry A Rodionov
Journal:  Front Mol Biosci       Date:  2022-08-11

6.  Identifying a 6-Gene Prognostic Signature for Lung Adenocarcinoma Based on Copy Number Variation and Gene Expression Data.

Authors:  Yisheng Huang; Liling Qiu; Xiaoye Liang; Jing Zhao; Haoting Chen; Zhiqiang Luo; Wanzhen Li; Xiaohua Lin; Jingjie Jin; Jian Huang; Gong Zhang
Journal:  Oxid Med Cell Longev       Date:  2022-09-28       Impact factor: 7.310

  6 in total

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