Geoffrey C S Smith1, Victor Liu2, Patrick H Lam3. 1. Department of Orthopaedic Surgery and Sutherland Clinical School, Sydney, Australia; University of New South Wales, Sydney, Australia. Electronic address: admin@drgeoffreysmith.com.au. 2. University of New South Wales, Sydney, Australia. 3. Orthopaedic Research Institute, St. George Hospital, Sydney, Australia.
Abstract
PURPOSE: To determine whether a high critical shoulder angle (CSA) is associated with symptomatic full-thickness rotator cuff (RC) tears and/or whether a low CSA is associated with primary glenohumeral osteoarthritis (GHOA). METHODS: A systematic review was performed following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. All observational studies that examined an association between CSA and full-thickness RC tears and/or primary GHOA were included. A primary meta-analysis was performed including all studies that met the inclusion criteria regardless of radiographic quality. A secondary meta-analysis was performed to explore the hypothesis that radiographic quality was a source of heterogeneity, which excluded those studies in which radiograph quality was not strictly defined and controlled. RESULTS: For the primary meta-analysis, 11 studies met the inclusion criteria for RC tears and 5 for primary GHOA. The CSA was greater in the RC tear group than the control group (mean difference 4.03°, 95% confidence interval 2.95°-5.11, 95% prediction interval 0.0487°-8.01°; P < .001). The CSA was lower in the GHOA group than the control group (mean difference -3.98°, 95% confidence interval -5.66° to -2.31°, 95% prediction interval -10.2° to -2.19°; P < .001).A high level of heterogeneity was observed in the RC tear analysis (I2 = 88.4), which decreased after the exclusion of 5 studies based on radiographic quality (I2 = 75.3). A high level of heterogeneity also was observed in the primary GHOA analysis (I2 = 87.3), which decreased after the exclusion of 2 studies based on the radiographic quality (I2 = 48.2). CONCLUSIONS: There is a reciprocal change in magnitude of the CSA when evaluating symptomatic full-thickness RC tears versus primary GHOA as compared with control subjects. Radiographic quality is a source of heterogeneity in studies that investigate a link between CSA and RC tears and primary GHOA. LEVEL OF EVIDENCE: Level III, systematic review and meta-analysis of Level III studies.
PURPOSE: To determine whether a high critical shoulder angle (CSA) is associated with symptomatic full-thickness rotator cuff (RC) tears and/or whether a low CSA is associated with primary glenohumeral osteoarthritis (GHOA). METHODS: A systematic review was performed following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. All observational studies that examined an association between CSA and full-thickness RC tears and/or primary GHOA were included. A primary meta-analysis was performed including all studies that met the inclusion criteria regardless of radiographic quality. A secondary meta-analysis was performed to explore the hypothesis that radiographic quality was a source of heterogeneity, which excluded those studies in which radiograph quality was not strictly defined and controlled. RESULTS: For the primary meta-analysis, 11 studies met the inclusion criteria for RC tears and 5 for primary GHOA. The CSA was greater in the RC tear group than the control group (mean difference 4.03°, 95% confidence interval 2.95°-5.11, 95% prediction interval 0.0487°-8.01°; P < .001). The CSA was lower in the GHOA group than the control group (mean difference -3.98°, 95% confidence interval -5.66° to -2.31°, 95% prediction interval -10.2° to -2.19°; P < .001).A high level of heterogeneity was observed in the RC tear analysis (I2 = 88.4), which decreased after the exclusion of 5 studies based on radiographic quality (I2 = 75.3). A high level of heterogeneity also was observed in the primary GHOA analysis (I2 = 87.3), which decreased after the exclusion of 2 studies based on the radiographic quality (I2 = 48.2). CONCLUSIONS: There is a reciprocal change in magnitude of the CSA when evaluating symptomatic full-thickness RC tears versus primary GHOA as compared with control subjects. Radiographic quality is a source of heterogeneity in studies that investigate a link between CSA and RC tears and primary GHOA. LEVEL OF EVIDENCE: Level III, systematic review and meta-analysis of Level III studies.