Literature DB >> 31901298

Histone Lactylation: A New Role for Glucose Metabolism.

Maria V Liberti1, Jason W Locasale2.   

Abstract

Lactate is an end product of glucose metabolism, which serves metabolic and nonmetabolic functions. A new study by Zhang et al. establishes a novel function for lactate whereby it is utilized in a new histone modification, histone lysine lactylation, to regulate gene expression in macrophages.
Copyright © 2019 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Warburg effect; histone lactylation; lactate; macrophage polarization

Year:  2019        PMID： 31901298     DOI： 10.1016/j.tibs.2019.12.004

Source DB:  PubMed          Journal:  Trends Biochem Sci        ISSN： 0968-0004            Impact factor:   13.807


  14 in total

Review 1.  Lactylation may be a Novel Posttranslational Modification in Inflammation in Neonatal Hypoxic-Ischemic Encephalopathy.

Authors:  Yue Zhou; Li Yang; Xiaoying Liu; Hao Wang
Journal:  Front Pharmacol       Date:  2022-06-02       Impact factor: 5.988

Review 2.  Glucose Metabolism, Neural Cell Senescence and Alzheimer's Disease.

Authors:  Qianqian Wang; Linyan Duan; Xingfan Li; Yifu Wang; Wenna Guo; Fangxia Guan; Shanshan Ma
Journal:  Int J Mol Sci       Date:  2022-04-14       Impact factor: 6.208

Review 3.  Lactate in Sarcoma Microenvironment: Much More than just a Waste Product.

Authors:  Maria Letizia Taddei; Laura Pietrovito; Angela Leo; Paola Chiarugi
Journal:  Cells       Date:  2020-02-24       Impact factor: 6.600

Review 4.  The Role of Posttranslational Modification and Mitochondrial Quality Control in Cardiovascular Diseases.

Authors:  Jinlin Liu; Li Zhong; Rui Guo
Journal:  Oxid Med Cell Longev       Date:  2021-02-18       Impact factor: 6.543

Review 5.  Interplay Among Metabolism, Epigenetic Modifications, and Gene Expression in Cancer.

Authors:  Miaomiao Huo; Jingyao Zhang; Wei Huang; Yan Wang
Journal:  Front Cell Dev Biol       Date:  2021-12-24

6.  Lactate Activates Germline and Cleavage Embryo Genes in Mouse Embryonic Stem Cells.

Authors:  Qing Tian; Li-Quan Zhou
Journal:  Cells       Date:  2022-02-04       Impact factor: 6.600

Review 7.  Lactylation, a Novel Metabolic Reprogramming Code: Current Status and Prospects.

Authors:  An-Na Chen; Yan Luo; Yu-Han Yang; Jian-Tao Fu; Xiu-Mei Geng; Jun-Ping Shi; Jin Yang
Journal:  Front Immunol       Date:  2021-06-10       Impact factor: 7.561

Review 8.  Epigenetic strategies to boost CAR T cell therapy.

Authors:  Behnia Akbari; Navid Ghahri-Saremi; Tahereh Soltantoyeh; Jamshid Hadjati; Saba Ghassemi; Hamid Reza Mirzaei
Journal:  Mol Ther       Date:  2021-08-06       Impact factor: 12.910

Review 9.  Crosstalk Between Staphylococcus aureus and Innate Immunity: Focus on Immunometabolism.

Authors:  Christopher M Horn; Tammy Kielian
Journal:  Front Immunol       Date:  2021-02-05       Impact factor: 7.561

Review 10.  Impact of Physical Activity and Exercise on the Epigenome in Skeletal Muscle and Effects on Systemic Metabolism.

Authors:  Julio Plaza-Diaz; David Izquierdo; Álvaro Torres-Martos; Aiman Tariq Baig; Concepción M Aguilera; Francisco Javier Ruiz-Ojeda
Journal:  Biomedicines       Date:  2022-01-07
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