| Literature DB >> 3189965 |
G Rolla1, C Bucca, E Caria, W Arossa, M Bugiani, L Cesano, A Caropreso.
Abstract
The bronchodilating effect of magnesium sulfate (MgSO4) was studied in ten asthmatic patients with moderate to severe airway obstruction. Two grams of MgSO4 or saline in double-blind crossover design was administered IV for 20 minutes (0.40 mmol/min) and forced expiratory capacity and forced expiratory volume in one second (FEV1) were studied at intervals. Only at the end of MgSO4 infusion did FEV1 increase significantly (109% of initial values). The bronchodilating effect was short lasting and far less than that observed after salbutamol.Entities:
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Year: 1988 PMID： 3189965
Source DB: PubMed Journal: Ann Allergy ISSN： 0003-4738