Literature DB >> 31899488

Differential Expression Gene Explorer (DrEdGE): a tool for generating interactive online visualizations of gene expression datasets.

Sophia C Tintori1, Patrick Golden2, Bob Goldstein1.   

Abstract

SUMMARY: Differential Expression Gene Explorer (DrEdGE) is a web-based tool that guides genomicists through easily creating interactive online data visualizations, which colleagues can query according to their own conditions to discover genes, samples or patterns of interest. We demonstrate DrEdGE's features with three example websites generated from publicly available datasets-human neuronal tissue, mouse embryonic tissue and Caenorhabditis elegans whole embryos. DrEdGE increases the utility of large genomics datasets by removing technical obstacles to independent exploration.
AVAILABILITY AND IMPLEMENTATION: Freely available at http://dredge.bio.unc.edu. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.
© The Author(s) 2020. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

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Year:  2020        PMID: 31899488      PMCID: PMC7178403          DOI: 10.1093/bioinformatics/btz972

Source DB:  PubMed          Journal:  Bioinformatics        ISSN: 1367-4803            Impact factor:   6.937


  8 in total

1.  Gene Expression Omnibus: NCBI gene expression and hybridization array data repository.

Authors:  Ron Edgar; Michael Domrachev; Alex E Lash
Journal:  Nucleic Acids Res       Date:  2002-01-01       Impact factor: 16.971

2.  The human genome browser at UCSC.

Authors:  W James Kent; Charles W Sugnet; Terrence S Furey; Krishna M Roskin; Tom H Pringle; Alan M Zahler; David Haussler
Journal:  Genome Res       Date:  2002-06       Impact factor: 9.043

3.  Data sharing: An open mind on open data.

Authors:  Virginia Gewin
Journal:  Nature       Date:  2016-01-07       Impact factor: 49.962

4.  Genome browsing with Ensembl: a practical overview.

Authors:  Giulietta Spudich; Xosé M Fernández-Suárez; Ewan Birney
Journal:  Brief Funct Genomic Proteomic       Date:  2007-10-29

5.  A Transcriptional Lineage of the Early C. elegans Embryo.

Authors:  Sophia C Tintori; Erin Osborne Nishimura; Patrick Golden; Jason D Lieb; Bob Goldstein
Journal:  Dev Cell       Date:  2016-08-22       Impact factor: 12.270

6.  SCIENTIFIC STANDARDS. Promoting an open research culture.

Authors:  B A Nosek; G Alter; G C Banks; D Borsboom; S D Bowman; S J Breckler; S Buck; C D Chambers; G Chin; G Christensen; M Contestabile; A Dafoe; E Eich; J Freese; R Glennerster; D Goroff; D P Green; B Hesse; M Humphreys; J Ishiyama; D Karlan; A Kraut; A Lupia; P Mabry; T A Madon; N Malhotra; E Mayo-Wilson; M McNutt; E Miguel; E Levy Paluck; U Simonsohn; C Soderberg; B A Spellman; J Turitto; G VandenBos; S Vazire; E J Wagenmakers; R Wilson; T Yarkoni
Journal:  Science       Date:  2015-06-26       Impact factor: 47.728

7.  The time-resolved transcriptome of C. elegans.

Authors:  Max E Boeck; Chau Huynh; Lou Gevirtzman; Owen A Thompson; Guilin Wang; Dionna M Kasper; Valerie Reinke; LaDeana W Hillier; Robert H Waterston
Journal:  Genome Res       Date:  2016-08-16       Impact factor: 9.043

8.  An integrated encyclopedia of DNA elements in the human genome.

Authors: 
Journal:  Nature       Date:  2012-09-06       Impact factor: 49.962

  8 in total
  2 in total

1.  ideal: an R/Bioconductor package for interactive differential expression analysis.

Authors:  Federico Marini; Jan Linke; Harald Binder
Journal:  BMC Bioinformatics       Date:  2020-12-09       Impact factor: 3.169

2.  High neural activity accelerates the decline of cognitive plasticity with age in Caenorhabditis elegans.

Authors:  Qiaochu Li; Daniel-Cosmin Marcu; Ottavia Palazzo; Frances Turner; Declan King; Tara L Spires-Jones; Melanie I Stefan; Karl Emanuel Busch
Journal:  Elife       Date:  2020-11-24       Impact factor: 8.713

  2 in total

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