Literature DB >> 31899404

Risk Factors for Negative Global Treatment Outcomes in Lumbar Spinal Stenosis Surgery: A Mixed Effects Model Analysis of Data from an International Spine Registry.

Emin Aghayev1, Anne F Mannion2, Tamas F Fekete2, Sven Janssen3, Kelly Goodwin4, Marcel Zwahlen4, Ulrich Berlemann5, Tobias Lorenz3.   

Abstract

OBJECTIVE: To determine risk factors for negative global treatment outcomes as self-assessed by patients undergoing surgical treatment for lumbar spinal stenosis (LSS).
METHODS: Patients from the Spine Tango registry undergoing first-time surgery for LSS were analyzed. The primary outcome was global treatment outcomes measured at the last available follow-up ≥3 months postoperatively using a single question rating how much the operation had helped the patient's back problem (negative = no change/operation made things worse). A 2-level logistic mixed effects model with the treating department as the random effect was used to assess factors associated with a negative outcome.
RESULTS: A total of 4504 patients from 39 departments in 10 countries were included. Overall, 14.4% of patients reported a negative global treatment outcome after an average follow-up of 1.3 years. In patients with dominant leg pain, negative outcome was associated with higher baseline back pain; in those with dominant back pain, it was associated with higher baseline back pain, ASA (American Society of Anesthesiologists) ≥3, lower age, not having rigid stabilization, not having disc herniation, and the vertebral level of the most severely affected segment (L5/S1 vs. L3/4). Four departments had significantly higher odds of a negative outcome, whereas 1 department had significantly lower odds. Three out of the 4 negative effects were related to 2 departments from 1 country.
CONCLUSIONS: LSS surgery fails to help at least 1 in 10 patients. High baseline back pain is the most important factor associated with a negative treatment outcome. Department-level and potentially country-level factors of unknown origin explained a nonnegligible variation in the treatment results.
Copyright © 2019 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Lumbar spinal stenosis; Mixed effects model; Negative outcome; Spine Tango

Mesh:

Year:  2019        PMID: 31899404     DOI: 10.1016/j.wneu.2019.12.147

Source DB:  PubMed          Journal:  World Neurosurg        ISSN: 1878-8750            Impact factor:   2.104


  4 in total

1.  Risk Factors for Failing to Reach a Minimal Clinically Important Difference Following Minimally Invasive Lumbar Decompression.

Authors:  Elliot D K Cha; Conor P Lynch; Cara E Geoghegan; Caroline N Jadczak; Shruthi Mohan; Kern Singh
Journal:  Int J Spine Surg       Date:  2022-02-17

Review 2.  The influence of comorbidities on the treatment outcome in symptomatic lumbar spinal stenosis: A systematic review and meta-analysis.

Authors:  Amandine Bays; Andrea Stieger; Ulrike Held; Lisa J Hofer; Eva Rasmussen-Barr; Florian Brunner; Johann Steurer; Maria M Wertli
Journal:  N Am Spine Soc J       Date:  2021-06-02

3.  Prediction of Long-Term Recovery From Disability Using Hemoglobin-Based Models: Results From a Cohort of 1,392 Patients Undergoing Spine Surgery.

Authors:  Matteo Briguglio; Paolo Perazzo; Francesco Langella; Tiziano Crespi; Elena De Vecchi; Patrizia Riso; Marisa Porrini; Laura Scaramuzzo; Roberto Bassani; Marco Brayda-Bruno; Giuseppe Banfi; Pedro Berjano
Journal:  Front Surg       Date:  2022-03-16

4.  Lower Extremity Arterial Disease and Lumbar Spinal Stenosis: A Study of Exercise-Induced Arterial Ischemia in 5197 Patients Complaining of Claudication.

Authors:  Simon Lecoq; Jeanne Hersant; Mathieu Feuilloy; Henri-François Parent; Samir Henni; Pierre Abraham
Journal:  J Clin Med       Date:  2022-09-22       Impact factor: 4.964

  4 in total

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