Literature DB >> 31898631

The effects of obesity on pulmonary function in adults with asthma.

Mahmood Dhahir Al-Mendalawi1.   

Abstract

Entities:  

Year:  2020        PMID: 31898631      PMCID: PMC6961105          DOI: 10.4103/lungindia.lungindia_406_19

Source DB:  PubMed          Journal:  Lung India        ISSN: 0970-2113


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Sir, I read with interest the distinguished study by Özbey et al.[1] published in September–October 2019 issue of the Lung India. The authors studied the effects of nutritional habits and obesity on pulmonary functions and control of asthma in a cohort of Turkish patients with asthma who aged between 20 and 65 years. On employing spirometery to assess pulmonary function tests (PFTs), they found that the obese respondents had a lower mean forced vital capacity (FVC), forced expiratory volume in 1 s (FEV1), midexpiratory flow (MEF) between 25% and 75% of the maximal expiration (MEF25–75), MEF75, MEF50, MEF25, and FEV1/FVC values when compared to the respondents with normal weight (P < 0.05).[1] Apart from few study limitations mentioned by the authors, I presume that the following methodological limitation is additionally relevant. It is worthy to mention that interpreting PFT in a given population needs prediction equations for spirometery based on certain determinants such as age, gender, and height for that population.[2] Indeed, many adult populations-specific references equations for spirometric indices have been formulated to be employed in the researches and clinical fields.[34] In the methodology, the authors did not mention which spirometric reference intervals were used to interpret PFT in the studied cohort. To my knowledge, spirometric standards for adult Turkish population have been already evaluated.[5] I presume that employing these national standards in the study methodology could provide more accurate idea on the influence of obesity on pulmonary functions and asthma control. Despite study limitations, the study results urge the need for weight reduction in asthmatic patients to preserve lung function and improve the quality of life.

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Conflicts of interest

There are no conflicts of interest.
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4.  Reference equations for spirometric indices from a sample of the general adult population in Nigeria.

Authors:  Ademola Emmanuel Fawibe; Louis O Odeigah; Mohammed J Saka
Journal:  BMC Pulm Med       Date:  2017-03-06       Impact factor: 3.317

5.  The effects of obesity on pulmonary function in adults with asthma.

Authors:  Ümüş Özbey; Uçar Ucar; Aliye Gamze Calis
Journal:  Lung India       Date:  2019 Sep-Oct
  5 in total

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