Literature DB >> 31897973

Asthma and Indoor Environment: Usefulness of a Global Allergen Avoidance Method on Asthma Control and Exposure to Molds.

Jean-Pierre Gangneux1,2, Matthieu Bouvrais3, Sophie Frain4, Hugues Morel5, Séverine Deguen6, Sylviane Chevrier7, Pierre Le Cann6.   

Abstract

The usefulness and feasibility of a global allergens avoidance method with counselors visiting patients' home for allergens measures and adapted advices were prospectively evaluated through asthma control and environment evaluation. Twenty seven patients were prospectively included and compared to a cohort of 30 control patients. The level of control of asthma at inclusion and after 1 year was evaluated by the clinical signs, the evolution of the FEV1, and the healthcare use. Environmental measurements included the fungal load of 5 surfaces of the dwellings and the evaluation of moisture. A significant clinical improvement in the population that benefited from the home counselors visit was observed compared to the baseline (p < 0.0001), as well as a decreased number of hospitalizations for asthma and of the consumption of anti-asthma drugs (p < 0.01). Dampness markers slightly improved with an improvement of the fungal loads in two-third of the dwellings.

Entities:  

Keywords:  Allergens; Asthma; Home intervention; Molds; Pollutants

Year:  2020        PMID: 31897973     DOI: 10.1007/s11046-019-00417-9

Source DB:  PubMed          Journal:  Mycopathologia        ISSN: 0301-486X            Impact factor:   2.574


  14 in total

Review 1.  Risk factors for asthma: is prevention possible?

Authors:  Richard Beasley; Alex Semprini; Edwin A Mitchell
Journal:  Lancet       Date:  2015-09-12       Impact factor: 79.321

2.  Asthma cases attributable to atopy: results from the Third National Health and Nutrition Examination Survey.

Authors:  Samuel J Arbes; Peter J Gergen; Ben Vaughn; Darryl C Zeldin
Journal:  J Allergy Clin Immunol       Date:  2007-09-24       Impact factor: 10.793

3.  Association of household cleaning agents and disinfectants with asthma in young German adults.

Authors:  Tobias Weinmann; Jessica Gerlich; Sabine Heinrich; Dennis Nowak; Erika von Mutius; Christian Vogelberg; Jon Genuneit; Stefanie Lanzinger; Saba Al-Khadra; Tina Lohse; Irina Motoc; Viola Walter; Katja Radon
Journal:  Occup Environ Med       Date:  2017-05-08       Impact factor: 4.402

4.  Correlation between Environmental Relative Moldiness Index (ERMI) values in French dwellings and other measures of fungal contamination.

Authors:  Delphine Méheust; Jean-Pierre Gangneux; Tiina Reponen; Larry Wymer; Stephen Vesper; Pierre Le Cann
Journal:  Sci Total Environ       Date:  2012-09-27       Impact factor: 7.963

5.  Possible application of the Environmental Relative Moldiness Index in France: a pilot study in Brittany.

Authors:  Delphine Méheust; Pierre Le Cann; Tiina Reponen; Jennie Wakefield; Stephen Vesper; Jean-Pierre Gangneux
Journal:  Int J Hyg Environ Health       Date:  2012-07-27       Impact factor: 5.840

Review 6.  The link between fungi and severe asthma: a summary of the evidence.

Authors:  D W Denning; B R O'Driscoll; C M Hogaboam; P Bowyer; R M Niven
Journal:  Eur Respir J       Date:  2006-03       Impact factor: 16.671

7.  Current asthma in schoolchildren is related to fungal spores in classrooms.

Authors:  Chi-Hsien Chen; H Jasmine Chao; Chang-Chuan Chan; Bing-Yu Chen; Yue Leon Guo
Journal:  Chest       Date:  2014-07       Impact factor: 9.410

Review 8.  Microbes, allergic sensitization, and the natural history of asthma.

Authors:  Halie M Anderson; Daniel J Jackson
Journal:  Curr Opin Allergy Clin Immunol       Date:  2017-04

Review 9.  Home Environmental Interventions for the Prevention or Control of Allergic and Respiratory Diseases: What Really Works.

Authors:  Pierre Le Cann; Hélène Paulus; Philippe Glorennec; Barbara Le Bot; Sophie Frain; Jean Pierre Gangneux
Journal:  J Allergy Clin Immunol Pract       Date:  2016-09-21

10.  Cleaning at Home and at Work in Relation to Lung Function Decline and Airway Obstruction.

Authors:  Øistein Svanes; Randi J Bertelsen; Stein H L Lygre; Anne E Carsin; Josep M Antó; Bertil Forsberg; José M García-García; José A Gullón; Joachim Heinrich; Mathias Holm; Manolis Kogevinas; Isabel Urrutia; Bénédicte Leynaert; Jesús M Moratalla; Nicole Le Moual; Theodore Lytras; Dan Norbäck; Dennis Nowak; Mario Olivieri; Isabelle Pin; Nicole Probst-Hensch; Vivi Schlünssen; Torben Sigsgaard; Trude D Skorge; Simona Villani; Debbie Jarvis; Jan P Zock; Cecilie Svanes
Journal:  Am J Respir Crit Care Med       Date:  2018-05-01       Impact factor: 21.405

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  1 in total

1.  Metagenomic Characterization of Indoor Dust Bacterial and Fungal Microbiota in Homes of Asthma and Non-asthma Patients Using Next Generation Sequencing.

Authors:  Jean-Pierre Gangneux; Mohamed Sassi; Pierre Lemire; Pierre Le Cann
Journal:  Front Microbiol       Date:  2020-07-30       Impact factor: 5.640

  1 in total

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