Literature DB >> 31897669

Genetic characterization of 19 X-STRs in Sierra Leone population from Freetown.

Lin Lin1,2, Jienan Li3, Yize Hu4, Han Wang5, Foday Ambrose Marah6, Moses Moseray7,8, Aliye Kureshi3, Chudong Wang3, Moutanou Modeste Judes Zeye3,9, Lagabaiyila Zha10,11.   

Abstract

A total of 550 individuals (265 males and 285 females) from Sierra Leone, a west-African coastal country, were genotyped using the Microreader™ 19X ID System kit. No significant deviations from the Hardy-Weinberg equilibrium were observed. A total of 250 alleles were identified with corresponding allele frequencies spanning from 0.0012 to 0.6762. PIC of the loci ranged from 0.4615 to 0.9481. The CPE, CPDF, and CPDM were 0.9999997856, 0.999999999999999999995774, and 0.999999999998997, respectively. The highly combined MECKruger, MECKishida, MECDesmarais, and MECDesmarais Duo were achieved as 0.99999992508, 0.999999999990802, 0.999999999990836, and 0.99999998412, respectively. Genetic comparisons revealed that genetic homogeneity existed in similar ethno origin or geographic origin populations. This is a pioneering genetic investigation using the Microreader™ 19X ID System kit in the population of Sierra Leone.

Keywords:  Population study; Short tandem repeat; Sierra Leone; X chromosome

Mesh:

Year:  2020        PMID: 31897669     DOI: 10.1007/s00414-019-02243-6

Source DB:  PubMed          Journal:  Int J Legal Med        ISSN: 0937-9827            Impact factor:   2.686


  5 in total

1.  A new Web site compiling forensic chromosome X research is now online.

Authors:  Reinhard Szibor; Sandra Hering; Jeanett Edelmann
Journal:  Int J Legal Med       Date:  2005-08-25       Impact factor: 2.686

Review 2.  X-chromosomal markers: past, present and future.

Authors:  Reinhard Szibor
Journal:  Forensic Sci Int Genet       Date:  2007-04-27       Impact factor: 4.882

Review 3.  Population genetics--making sense out of sequence.

Authors:  A Chakravarti
Journal:  Nat Genet       Date:  1999-01       Impact factor: 38.330

4.  POPTREE2: Software for constructing population trees from allele frequency data and computing other population statistics with Windows interface.

Authors:  Naoko Takezaki; Masatoshi Nei; Koichiro Tamura
Journal:  Mol Biol Evol       Date:  2009-12-18       Impact factor: 16.240

5.  Selection in finite populations with multiple alleles. 3. Genetic divergence with centripetal selection and mutation.

Authors:  B D Latter
Journal:  Genetics       Date:  1972-03       Impact factor: 4.562

  5 in total
  1 in total

1.  Forensic characteristics and genetic structure of 18 autosomal STR loci in the Sierra Leone population.

Authors:  Jienan Li; Lagabaiyila Zha
Journal:  Int J Legal Med       Date:  2021-01-06       Impact factor: 2.686

  1 in total

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