Literature DB >> 31897535

Pronounced influence of presystemic metabolism on the metabolic disposition of imrecoxib in renally impaired patients.

Nuggehally R Srinivas1,2.   

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Year:  2020        PMID： 31897535     DOI： 10.1007/s00228-019-02824-9

Source DB:  PubMed          Journal:  Eur J Clin Pharmacol        ISSN： 0031-6970            Impact factor:   2.953


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  13 in total

1.  Synthesis and anti-inflammatory activity of the major metabolites of imrecoxib.

Authors:  Zhiqiang Feng; Fengming Chu; Zongru Guo; Piaoyang Sun
Journal:  Bioorg Med Chem Lett       Date:  2009-02-27       Impact factor: 2.823

2.  The Role of the Kidney in Drug Elimination: Transport, Metabolism, and the Impact of Kidney Disease on Drug Clearance.

Authors:  J O Miners; X Yang; K M Knights; L Zhang
Journal:  Clin Pharmacol Ther       Date:  2017-07-26       Impact factor: 6.875

Review 3.  Altered disposition of drugs in acute renal failure rat models: drug development strategies and perspectives.

Authors:  Nuggehally R Srinivas
Journal:  Arzneimittelforschung       Date:  2010

4.  Differences in the In Vivo and In Vitro Metabolism of Imrecoxib in Humans: Formation of the Rate-Limiting Aldehyde Intermediate.

Authors:  Xiangyu Hou; Jialan Zhou; Songda Yu; Lei Zhou; Yifan Zhang; Dafang Zhong; Xiaoyan Chen
Journal:  Drug Metab Dispos       Date:  2018-07-06       Impact factor: 3.922

Review 5.  The effects of acute renal failure on drug metabolism.

Authors:  Barbara J Philips; Katie Lane; John Dixon; Iain Macphee
Journal:  Expert Opin Drug Metab Toxicol       Date:  2013-09-28       Impact factor: 4.481

6.  Metabolism and excretion of imrecoxib in rat.

Authors:  H Xu; Y Zhang; Y Sun; P Zhang; F Chu; Z Guo; H Zhang; D Zhong
Journal:  Xenobiotica       Date:  2006-05       Impact factor: 1.908

7.  [Investigation on the hydroxylation metabolism of imrecoxib in vitro by using recombinant human CYPs].

Authors:  Qiang Li; Hai-Hua Huang; Yu Dong; Da-Fang Zhong
Journal:  Yao Xue Xue Bao       Date:  2005-10

Review 8.  Use of Cocktail Probe Drugs for Indexing Cytochrome P450 Enzymes in Clinical Pharmacology Studies - Review of Case Studies.

Authors:  Poonam Giri; Harilal Patel; Nuggehally R Srinivas
Journal:  Drug Metab Lett       Date:  2019

9.  Imrecoxib: a novel and selective cyclooxygenase 2 inhibitor with anti-inflammatory effect.

Authors:  Xiao-hong Chen; Jin-ye Bai; Fang Shen; Ai-ping Bai; Zong-ru Guo; Gui-fang Cheng
Journal:  Acta Pharmacol Sin       Date:  2004-07       Impact factor: 6.150

Review 10.  Effects of chronic kidney disease and uremia on hepatic drug metabolism and transport.

Authors:  Catherine K Yeung; Danny D Shen; Kenneth E Thummel; Jonathan Himmelfarb
Journal:  Kidney Int       Date:  2013-10-16       Impact factor: 10.612
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