Literature DB >> 31895157

Can chronic oral inflammation and masticatory dysfunction contribute to cognitive impairment?

Matthew R Nangle1, Nithin Manchery.   

Abstract

PURPOSE OF REVIEW: This article provides an overview of current literature focused on oral health and cognitive impairment in older adulthood, focusing in particular on whether oral inflammation, tooth loss and masticatory dysfunction might increase the risk of cognitive impairment in this age group. RECENT
FINDINGS: There is now general acceptance that cognitive impairment contributes to poor oral health, largely through detrimental changes in behaviours related to maintaining good oral hygiene. There is more limited evidence for the reverse causal direction, but at least some studies now suggest that inflammatory mechanisms, tooth loss and masticatory dysfunction each have the potential to contribute to cognitive decline.
SUMMARY: Poorer oral health significantly correlates with cognitive dysfunction, and at least some studies suggest that there may be a bi-directional causal relationship. Randomized controlled trials assessing cognitive abilities in relation to oral hygiene or oral health interventions, or provision of removable or fixed (implant-supported) dentures, are encouraged.

Entities:  

Mesh:

Year:  2020        PMID: 31895157     DOI: 10.1097/YCO.0000000000000581

Source DB:  PubMed          Journal:  Curr Opin Psychiatry        ISSN: 0951-7367            Impact factor:   4.741


  4 in total

1.  Cognitive function and oral health in relapsing-remitting multiple sclerosis.

Authors:  Nithin Manchery; Julie D Henry; Andrew Swayne; Reuben Beer; Stefan Blum; Matthew R Nangle
Journal:  Clin Oral Investig       Date:  2021-11-13       Impact factor: 3.573

2.  Combined association of cognitive impairment and poor oral health on mortality risk in older adults: Results from the NHANES with 15 years of follow-up.

Authors:  An Li; Yuntao Chen; Anita Visser; Luc A M Marks; Geerten-Has E Tjakkes
Journal:  J Periodontol       Date:  2021-11-12       Impact factor: 4.494

3.  Memory decline in older individuals predicts an objective indicator of oral health: findings from the Sydney Memory and Ageing Study.

Authors:  Nithin Manchery; Julie D Henry; Ben C P Lam; Nicole A Kochan; Alan Deutsch; Henry Brodaty; Perminder S Sachdev; Matthew R Nangle
Journal:  BMC Oral Health       Date:  2022-03-27       Impact factor: 2.757

4.  BMI, functional and cognitive status in a cohort of nonagenarians: results from the Mugello study.

Authors:  Monica Dinu; Barbara Colombini; Giuditta Pagliai; Federica Vannetti; Guido Pasquini; Raffaello Molino Lova; Francesca Cecchi; Sandro Sorbi; Francesco Sofi; Claudio Macchi
Journal:  Eur Geriatr Med       Date:  2020-10-21       Impact factor: 1.710

  4 in total

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