Anna Toscano1,2, Myriam Blanchin1, Marianne Bourdon1, Angélique Bonnaud Antignac1,3, Véronique Sébille4,5. 1. UMR INSERM 1246, SPHERE "methodS in patient-centered outcomes and HEalth ResEarch", University of Nantes, University of Tours, 22 boulevard Benoni Goullin, Nantes, France. 2. Department of Psychology, University of Turin, Turin, Italy. 3. Surgical Oncology Service, ICO Nantes, Saint Herblain, France. 4. UMR INSERM 1246, SPHERE "methodS in patient-centered outcomes and HEalth ResEarch", University of Nantes, University of Tours, 22 boulevard Benoni Goullin, Nantes, France. veronique.sebille@univ-nantes.fr. 5. Methodology and Biostatistics Unit, CHU of Nantes, Nantes, France. veronique.sebille@univ-nantes.fr.
Abstract
PURPOSE: A diagnosis of breast cancer or melanoma is a traumatic life event that patients have to face. However, their locus-of-control (LOC) beliefs and coping strategies as well as the associations with health-related quality of life (HRQoL) changes over time are still not well known and rarely compared by cancer site. METHODS: The objective of this longitudinal study was to assess the association of LOC (Cancer Locus-of-Control Scale) and coping (Brief Cope) changes, with change in HRQoL (EORTC QLQ-C30) over time in newly diagnosed breast cancer and melanoma patients at 1, 6, 12, and 24 month post-diagnosis. Mixed models were used to compare LOC and coping longitudinal changes as well as their associations with HRQoL changes in early-stage breast cancer and melanoma patients. RESULTS: Overall, 215 breast cancer and 78 melanoma patients participated in the study. At baseline, HRQoL levels were often higher for breast cancer compared to melanoma patients. For breast cancer and melanoma patients, negative coping strategies and perceived control over the course of illness were negatively and positively associated with HRQoL changes, respectively. For breast cancer patients only, emotional coping and internal causal attribution were negatively associated with HRQoL changes. For both cancer sites, living with a partner correlated with worse HRQoL. CONCLUSIONS: Understanding coping strategies and LOC beliefs used by patients soon after their cancer diagnosis and over the course of illness can help identifying psychological and supportive care to modify maladaptive thoughts and beliefs and promote more adaptive behaviors to ultimately improve patients' well-being and HRQoL.
PURPOSE: A diagnosis of breast cancer or melanoma is a traumatic life event that patients have to face. However, their locus-of-control (LOC) beliefs and coping strategies as well as the associations with health-related quality of life (HRQoL) changes over time are still not well known and rarely compared by cancer site. METHODS: The objective of this longitudinal study was to assess the association of LOC (Cancer Locus-of-Control Scale) and coping (Brief Cope) changes, with change in HRQoL (EORTC QLQ-C30) over time in newly diagnosed breast cancer and melanomapatients at 1, 6, 12, and 24 month post-diagnosis. Mixed models were used to compare LOC and coping longitudinal changes as well as their associations with HRQoL changes in early-stage breast cancer and melanomapatients. RESULTS: Overall, 215 breast cancer and 78 melanomapatients participated in the study. At baseline, HRQoL levels were often higher for breast cancer compared to melanomapatients. For breast cancer and melanomapatients, negative coping strategies and perceived control over the course of illness were negatively and positively associated with HRQoL changes, respectively. For breast cancerpatients only, emotional coping and internal causal attribution were negatively associated with HRQoL changes. For both cancer sites, living with a partner correlated with worse HRQoL. CONCLUSIONS: Understanding coping strategies and LOC beliefs used by patients soon after their cancer diagnosis and over the course of illness can help identifying psychological and supportive care to modify maladaptive thoughts and beliefs and promote more adaptive behaviors to ultimately improve patients' well-being and HRQoL.
Entities:
Keywords:
Breast cancer; Coping; Health-related quality of life; Locus of control; Longitudinal data; Melanoma
Authors: Alina Radicke; Claus Barkmann; Bonnie Adema; Anne Daubmann; Karl Wegscheider; Silke Wiegand-Grefe Journal: Int J Environ Res Public Health Date: 2021-01-06 Impact factor: 3.390
Authors: Katarina Veličković; Carl A K Borrebaeck; Pär-Ola Bendahl; Cecilia Hegardt; Per Johnsson; Corinna Richter; Lisa Rydén; Ingalill Rahm Hallberg Journal: Front Oncol Date: 2022-08-16 Impact factor: 5.738