Literature DB >> 3189355

Mortality among workers at a nuclear fuels production facility.

D L Cragle1, R W McLain, J R Qualters, J L Hickey, G S Wilkinson, W G Tankersley, C C Lushbaugh.   

Abstract

A retrospective cohort mortality study was conducted in a population of workers employed at a facility with the primary task of production of nuclear fuels and other materials. Data for hourly and salaried employees were analyzed separately by time period of first employment and length of employment. The hourly (N = 6,687 with 728 deaths) and salaried (N = 2,745 with 294 deaths) employees had a mortality experience comparable to that of the United States and, in fact, exhibited significant fewer deaths in many categories of diseases that are traditionally associated with the healthy worker effect. Specifically, fewer deaths were noted in the categories of all causes, all cancers, cancer of the digestive organs, lung cancer, brain cancer (hourly workers only), diabetes, all diseases of the circulatory system, all respiratory diseases, all digestive system diseases, all diseases of the genitourinary system (hourly only), and all external causes of death. A statistically significant, and as yet unexplained increase in leukemia mortality (6 observed vs. 2.18 expected) appeared among a subset of the hourly employees, first hired before 1955, and employed between 5-15 years.

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Year:  1988        PMID: 3189355     DOI: 10.1002/ajim.4700140404

Source DB:  PubMed          Journal:  Am J Ind Med        ISSN: 0271-3586            Impact factor:   2.214


  7 in total

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Authors:  Kim A Angelon-Gaetz; David B Richardson; Steve Wing
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2.  Case-control study of prostatic cancer in employees of the United Kingdom Atomic Energy Authority.

Authors:  C Rooney; V Beral; N Maconochie; P Fraser; G Davies
Journal:  BMJ       Date:  1993-11-27

3.  Wip1 abrogation decreases intestinal tumor frequency in APC(Min/+) mice irrespective of radiation quality.

Authors:  Shubhankar Suman; Bo-Hyun Moon; Hemang Thakor; Albert J Fornace; Kamal Datta
Journal:  Radiat Res       Date:  2014-08-12       Impact factor: 2.841

Review 4.  Epidemiology of accidental radiation exposures.

Authors:  E Cardis
Journal:  Environ Health Perspect       Date:  1996-05       Impact factor: 9.031

5.  Increased Transgenerational Intestinal Tumorigenesis in Offspring of Ionizing Radiation Exposed Parent APC1638N/+ Mice.

Authors:  Shubhankar Suman; Santosh Kumar; Bo-Hyun Moon; Albert J Fornace; Bhaskar V S Kallakury; Kamal Datta
Journal:  J Cancer       Date:  2017-07-01       Impact factor: 4.207

6.  Heavy ion radiation exposure triggered higher intestinal tumor frequency and greater β-catenin activation than γ radiation in APC(Min/+) mice.

Authors:  Kamal Datta; Shubhankar Suman; Bhaskar V S Kallakury; Albert J Fornace
Journal:  PLoS One       Date:  2013-03-21       Impact factor: 3.240

Review 7.  Colorectal Carcinogenesis, Radiation Quality, and the Ubiquitin-Proteasome Pathway.

Authors:  Kamal Datta; Shubhankar Suman; Santosh Kumar; Albert J Fornace
Journal:  J Cancer       Date:  2016-01-01       Impact factor: 4.207

  7 in total

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