Literature DB >> 3189340

HLA antigens in cardiomyopathic Chilean chagasics.

E Llop1, F Rothhammer, M Acuña, W Apt.   

Abstract

The distribution of HLA antigens in a sample of 124 Chagas serologically positive Chilean individuals was studied. The sample was subdivided according to the presence or absence of chagasic cardiomyopathy, in order to search for genetic differences associated with this pathological condition. The frequency of antigen B40 in the presence of antigen Cw3 was found to be significantly lower in subjects with cardiomyopathy. We tentatively suggest that the presence of these antigens among noncardiomyopathics is associated with a decreased susceptibility to develop chagasic cardiomyopathy in the Chilean population.

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Year:  1988        PMID： 3189340      PMCID： PMC1715553     

Source DB:  PubMed          Journal:  Am J Hum Genet        ISSN： 0002-9297            Impact factor:   11.025


  9 in total

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Authors:  F Rothhammer; E Llop; M Acuña; W Apt
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Journal:  Am J Phys Anthropol       Date:  1985-12       Impact factor: 2.868

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Authors:  A Arnaiz-Villena; S Rodriguez de Córdoba; F Vela; J C Pascual; J Cerveró; A Bootello
Journal:  Hum Genet       Date:  1981       Impact factor: 4.132

9.  Natural history of chagasic cardiopathy in Chile. Follow-up of 71 cases after 4 years.

Authors:  W Apt; A Arribada; L Cabrera; J Sandoval
Journal:  J Trop Med Hyg       Date:  1983-12
  9 in total
  5 in total

1.  Influence of acute-phase parasite load on pathology, parasitism, and activation of the immune system at the late chronic phase of Chagas' disease.

Authors:  C R Marinho; M R D'Império Lima; M G Grisotto; J M Alvarez
Journal:  Infect Immun       Date:  1999-01       Impact factor: 3.441

2.  Identification and partial characterization of Trypanosoma cruzi antigens recognized by T cells and immune sera from patients with Chagas' disease.

Authors:  R T Gazzinelli; V M Leme; J R Cancado; G Gazzinelli; J Scharfstein
Journal:  Infect Immun       Date:  1990-05       Impact factor: 3.441

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Authors:  N H Deghaide; R O Dantas; E A Donadi
Journal:  Dig Dis Sci       Date:  1998-02       Impact factor: 3.199

4.  Genetic susceptibility to Chagas disease cardiomyopathy: involvement of several genes of the innate immunity and chemokine-dependent migration pathways.

Authors:  Amanda Farage Frade; Cristina Wide Pissetti; Barbara Maria Ianni; Bruno Saba; Hui Tzu Lin-Wang; Luciana Gabriel Nogueira; Ariana de Melo Borges; Paula Buck; Fabrício Dias; Monique Baron; Ludmila Rodrigues Pinto Ferreira; Andre Schmidt; José Antonio Marin-Neto; Mario Hirata; Marcelo Sampaio; Abílio Fragata; Alexandre Costa Pereira; Eduardo Donadi; Jorge Kalil; Virmondes Rodrigues; Edecio Cunha-Neto; Christophe Chevillard
Journal:  BMC Infect Dis       Date:  2013-12-12       Impact factor: 3.090

Review 5.  Genetic susceptibility to Chagas disease: an overview about the infection and about the association between disease and the immune response genes.

Authors:  Christiane Maria Ayo; Márcia Machado de Oliveira Dalalio; Jeane Eliete Laguila Visentainer; Pâmela Guimarães Reis; Emília Ângela Sippert; Luciana Ribeiro Jarduli; Hugo Vicentin Alves; Ana Maria Sell
Journal:  Biomed Res Int       Date:  2013-08-28       Impact factor: 3.411
  5 in total

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