Literature DB >> 31890418

Levofloxacin-induced Psychosis in a Young Healthy Patient.

Michael Muradian1, Shaheena Khan1.   

Abstract

Levofloxacin is a fluoroquinolone antibiotic commonly used to treat a wide range of bacterial infections. It is normally well tolerated with the most common side effect being gastrointestinal distress. Severe side effects including neuropsychiatric symptoms are rare but have been observed even in patients who lack risk factors or are otherwise healthy. Healthcare providers should be aware of these effects and consider transitioning to other antibiotics in patients who develop psychosis or other neuropsychiatric symptoms after initiating this medication. Symptoms rapidly improve after discontinuation of the drug, so prompt recognition can reduce morbidity and mortality. We report a case of levofloxacin-induced psychosis in a young healthy female patient.
Copyright © 2019, Muradian et al.

Entities:  

Keywords:  acute psychosis; levofloxacin; medication side effects; neurotoxicity

Year:  2019        PMID: 31890418      PMCID: PMC6929259          DOI: 10.7759/cureus.6217

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  5 in total

1.  Leave the levofloxacin? A case report of levofloxacin-induced psychosis.

Authors:  Hailey Steuber; DeAndre Williams; Megan A Rech
Journal:  Am J Emerg Med       Date:  2018-05-18       Impact factor: 2.469

Review 2.  Comparison of side effects of levofloxacin versus other fluoroquinolones.

Authors:  C Carbon
Journal:  Chemotherapy       Date:  2001       Impact factor: 2.544

3.  Levofloxacin-induced delirium in a patient suffering from schizoaffective disorder and multiple sclerosis.

Authors:  Unax Lertxundi; Rafael Hernandez Palacios; Fernando Cibrián Gutierrez; Saioa Domingo-Echaburu; Monserrat García García; Carmelo Aguirre Gomez
Journal:  Curr Drug Saf       Date:  2013-07

4.  Acute psychotic symptoms following a single dose of levofloxacin.

Authors:  Larissa Takser; Roland Grad
Journal:  Clin Case Rep       Date:  2017-11-16

5.  Levofloxacin-induced acute psychosis.

Authors:  Nagaraja Moorthy; N Raghavendra; P N Venkatarathnamma
Journal:  Indian J Psychiatry       Date:  2008-01       Impact factor: 1.759

  5 in total

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