Literature DB >> 31889924

Single dose radiotherapy in soft tissue tumoral masses: just enough palliation.

Andrés Vargas1.   

Abstract

INTRODUCTION: Single fraction radiotherapy (SFR) is effective in palliation of symptoms related to advanced cancer. Despite this, several studies have shown that the trend towards multiple fraction treatment (MFR) is largely maintained. Even in patients with limited life expectancy, SFR is significantly underutilized in current practice. CASES DESCRIPTION: Four patients diagnosed with advanced cancer who developed soft tissue lesions were treated with SFR due to frailty and/or a poor performance status.
CONCLUSION: Despite the effectiveness of SFR is well-established in BM, its use in symptoms caused by soft tissue lesions have been underreported. SFR could be a good option for providing palliation in some patients, particularly in those who are frail or have a poor performance status.
© 2019 Greater Poland Cancer Centre. Published by Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Multifraction radiotherapy; Palliative radiotherapy; Single fraction radiotherapy; Soft tissue metastases

Year:  2019        PMID: 31889924      PMCID: PMC6931218          DOI: 10.1016/j.rpor.2019.12.010

Source DB:  PubMed          Journal:  Rep Pract Oncol Radiother        ISSN: 1507-1367


  13 in total

Review 1.  Palliative thoracic radiotherapy for lung cancer: a systematic review.

Authors:  Alysa Fairchild; Kristin Harris; Elizabeth Barnes; Rebecca Wong; Stephen Lutz; Andrea Bezjak; Patrick Cheung; Edward Chow
Journal:  J Clin Oncol       Date:  2008-08-20       Impact factor: 44.544

2.  Impact of a dedicated palliative radiation oncology service on the use of single fraction and hypofractionated radiation therapy among patients with bone metastases.

Authors:  Sonia Skamene; Isha Agarwal; Maggie Makar; Monica Krishnan; Alex Spektor; Lauren Hertan; Kent W Mouw; Allison Taylor; Sarah Noveroske Philbrick; Tracy Balboni
Journal:  Ann Palliat Med       Date:  2017-11-30

Review 3.  Palliative radiotherapy regimens for patients with thoracic symptoms from non-small cell lung cancer.

Authors:  Rosemary Stevens; Fergus Macbeth; Elizabeth Toy; Bernadette Coles; Jason F Lester
Journal:  Cochrane Database Syst Rev       Date:  2015-01-14

4.  8 Gy single fraction radiotherapy for the treatment of metastatic skeletal pain: randomised comparison with a multifraction schedule over 12 months of patient follow-up. Bone Pain Trial Working Party.

Authors: 
Journal:  Radiother Oncol       Date:  1999-08       Impact factor: 6.280

5.  The effect of a single fraction compared to multiple fractions on painful bone metastases: a global analysis of the Dutch Bone Metastasis Study.

Authors:  E Steenland; J W Leer; H van Houwelingen; W J Post; W B van den Hout; J Kievit; H de Haes; H Martijn; B Oei; E Vonk; E van der Steen-Banasik; R G Wiggenraad; J Hoogenhout; C Wárlám-Rodenhuis; G van Tienhoven; R Wanders; J Pomp; M van Reijn; I van Mierlo; E Rutten; J Leer; T van Mierlo
Journal:  Radiother Oncol       Date:  1999-08       Impact factor: 6.280

6.  Randomized trial of short- versus long-course radiotherapy for palliation of painful bone metastases.

Authors:  William F Hartsell; Charles B Scott; Deborah Watkins Bruner; Charles W Scarantino; Robert A Ivker; Mack Roach; John H Suh; William F Demas; Benjamin Movsas; Ivy A Petersen; Andre A Konski; Charles S Cleeland; Nora A Janjan; Michelle DeSilvio
Journal:  J Natl Cancer Inst       Date:  2005-06-01       Impact factor: 13.506

7.  Radiation therapy for the management of painful bone metastases: Results from a randomized trial.

Authors:  Lucia Gutiérrez Bayard; María Del Carmen Salas Buzón; Esther Angulo Paín; Lourdes de Ingunza Barón
Journal:  Rep Pract Oncol Radiother       Date:  2014-05-06

8.  Factors affecting the use of single-fraction radiotherapy for the palliation of bone metastases in Australia.

Authors:  A N Petrushevski; G S Gabriel; T P Hanna; S Allen; R W Allison; M B Barton
Journal:  Clin Oncol (R Coll Radiol)       Date:  2014-12-17       Impact factor: 4.126

9.  Palliative radiotherapy near the end of life.

Authors:  Susan Y Wu; Lisa Singer; Lauren Boreta; Michael A Garcia; Shannon E Fogh; Steve E Braunstein
Journal:  BMC Palliat Care       Date:  2019-03-23       Impact factor: 3.234

10.  A definition of "uncomplicated bone metastases" based on previous bone metastases radiation trials comparing single-fraction and multi-fraction radiation therapy.

Authors:  Paul M Cheon; Erin Wong; Nemica Thavarajah; Kristopher Dennis; Stephen Lutz; Liang Zeng; Edward Chow
Journal:  J Bone Oncol       Date:  2015-01-23       Impact factor: 4.072

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