| Literature DB >> 31889641 |
Valerio Pipola1, Stefano Boriani2, Riccardo Ghermandi3, Giuseppe Tedesco3, Gisberto Evangelisti3, Marco Girolami3, Alessandro Ricci4, Alessandro Gasbarrini3.
Abstract
The combination of surgery plus radiotherapy is a valid treatment option when en bloc resection with wide margins is not feasible. The aim of this paper is to show a novel technique for fixation of cervico-thoracic junction with carbon fiber reinforced peek pre-shaped rods with sublaminar bands in order to guarantee cervical spine stability and particle therapy efficacy. A 42 years-old man with a Sclerosing Epithelioid Fibrosarcoma (SEF) arising from C7, involving the right latero-cervical region from C5 to the apex of the right lung, underwent an en bloc resection with a double approach (anterior plus posterior). Fixation of cervical spine was achieved with composite PEEK/carbon fiber rods connected to C4 and T2 laminae with sublaminar bands. After surgery, the patient received 9 cycles of chemotherapy (cisplatin, etoposide and adriamycin) and proton therapy. At 2 years follow-up, no local recurrence was detected with implant stability demonstrating no mechanical failure. The main issues related to this case were: planning en bloc resection able to achieve an Enneking appropriate margin; incorporate in the decision making process the functional loss related to the sacrifice of neurological structures infiltrated by the tumor; establish a therapeutic strategy that included, in addition to surgery, adjuvant chemotherapy and radiotherapy for improving local and systemic control; stabilize with implants that do not interfere with accelerated particle radiotherapy.Entities:
Keywords: Carbon fiber reinforced peek rods; Cervical spine; Cervico-thoracic stabilization; En bloc resection; Sclerosing Epithelioid Fibrosarcoma; Sublaminar bands
Mesh:
Substances:
Year: 2019 PMID: 31889641 DOI: 10.1016/j.jocn.2019.12.035
Source DB: PubMed Journal: J Clin Neurosci ISSN: 0967-5868 Impact factor: 1.961