Literature DB >> 31888913

Inadvertent iatrogenic insulin detemir 1000 units overdose in a hospitalised patient.

Sudan Thapa1, Germin Fahim2, Sudha Ganne3.   

Abstract

A 69-year-old woman with uncontrolled type 2 diabetes mellitus was admitted in the hospital for the management of urosepsis. Patient was overdosed with detemir insulin 1000 units inadvertently. Care provider was confused with volume and dose of the insulin by using insulin vial. Blood sugars were monitored closely every 30 min-1 hour for 24 hours. Patient was treated with dextrose 5% and 10% continuous infusion; and hydrocortisone 75 mg every 6 hours for 24 hours. The lowest blood sugar reached was 142 mg/dL (7.9 mmo/L). Patient did not develop hypoglycaemia. Proper safety measures and mandatory nurse education about administration of insulin were implemented to prevent future occurrences. © BMJ Publishing Group Limited 2019. No commercial re-use. See rights and permissions. Published by BMJ.

Entities:  

Keywords:  diabetes; endocrine system; medical education

Mesh:

Substances:

Year:  2019        PMID: 31888913      PMCID: PMC6936578          DOI: 10.1136/bcr-2018-224999

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  7 in total

Review 1.  A Systematic Review on Insulin Overdose Cases: Clinical Course, Complications and Treatment Options.

Authors:  Nicklas Järvelä Johansen; Mikkel Bring Christensen
Journal:  Basic Clin Pharmacol Toxicol       Date:  2018-02-23       Impact factor: 4.080

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Authors:  C V Pollack
Journal:  J Emerg Med       Date:  1993 Mar-Apr       Impact factor: 1.484

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Journal:  Am J Ther       Date:  2011-09       Impact factor: 2.688

5.  Comparison of intravenous glucagon and dextrose in treatment of severe hypoglycemia in an accident and emergency department.

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Journal:  Diabetes Care       Date:  1987 Nov-Dec       Impact factor: 19.112

Review 6.  Treatment of sulfonylurea and insulin overdose.

Authors:  Wendy Klein-Schwartz; Gina L Stassinos; Geoffrey K Isbister
Journal:  Br J Clin Pharmacol       Date:  2016-01-06       Impact factor: 4.335

7.  Massive levemir (long-acting) insulin overdose: case report.

Authors:  Mamatha Oduru; Mahmood Ahmad
Journal:  Case Rep Med       Date:  2012-08-09
  7 in total

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