Wangming Sun1, Lingzhi Pan1,2, Weixi Zhang1. 1. The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China. 2. People's Hospital, Wenzhou, Zhejiang, China.
Abstract
Objective: Asthma seriously endangers the health of children. Re-hospitalization for childhood asthma consumes a large amount of medical and health resources. The present study aimed to assess the rates and risk factors for hospital readmission of children with acute asthma attacks in south China. Methods: We retrospectively enrolled 1702 acute asthma patients aged < 18 years from 1/1/2007 to 12/31/2015. Patients who were readmitted within one year after index hospital discharge were divided into a readmission group. Index hospitalization data were acquired from clinical records. Chi-square tests and multivariate logistic regression analyses were used to evaluate the risk factors. Results: There were 90 (5.29%) readmitted patients from 1702 acute asthma patients. Considering the large sample differences between readmitted and single-admitted patients, 123 single-admitted patients (1.5-fold as many as the readmitted group) were randomly selected. Further univariate Chi-square tests and multivariate logistic regression analyses showed that the predictors of readmission included eczema history (odds ratio (OR) 3.122, p = 0.003) and mycoplasma pneumoniae (MP) antibody immunoglobulin M(IgM) (OR 2.386, p = 0.037).Conclusions: Among the children admitted to a hospital in south China with acute asthma attacks, 5.29% were readmitted within the following year. Patients with history of eczema and positive MP antibody IgM had significantly increased the chances of one-year readmission, underlining the importance of targeted long-term postdischarge follow-up of these children.AbbreviationsUSUnited StatesICUIntensive Care UnitEOSEosinophiltIgETotal Immunoglobulin EsIgESpecific Immunoglobulin EMPMycoplasma pneumoniaeGINAthe Global Initiative for AsthmaIQRInterquartile RangeOROdds RatiosLOSLength of StayCIConfidence IntervalsRTIRespiratory Tract InfectionSABAShort Acting BronchodilatorICSInhaled CorticosteroidIUInternational UnitMLMilliliterIgMImmunoglobulin M.
Objective: Asthma seriously endangers the health of children. Re-hospitalization for childhood asthma consumes a large amount of medical and health resources. The present study aimed to assess the rates and risk factors for hospital readmission of children with acute asthma attacks in south China. Methods: We retrospectively enrolled 1702 acute asthmapatients aged < 18 years from 1/1/2007 to 12/31/2015. Patients who were readmitted within one year after index hospital discharge were divided into a readmission group. Index hospitalization data were acquired from clinical records. Chi-square tests and multivariate logistic regression analyses were used to evaluate the risk factors. Results: There were 90 (5.29%) readmitted patients from 1702 acute asthmapatients. Considering the large sample differences between readmitted and single-admitted patients, 123 single-admitted patients (1.5-fold as many as the readmitted group) were randomly selected. Further univariate Chi-square tests and multivariate logistic regression analyses showed that the predictors of readmission included eczema history (odds ratio (OR) 3.122, p = 0.003) and mycoplasma pneumoniae (MP) antibody immunoglobulin M(IgM) (OR 2.386, p = 0.037).Conclusions: Among the children admitted to a hospital in south China with acute asthma attacks, 5.29% were readmitted within the following year. Patients with history of eczema and positive MP antibody IgM had significantly increased the chances of one-year readmission, underlining the importance of targeted long-term postdischarge follow-up of these children.AbbreviationsUSUnited StatesICUIntensive Care UnitEOSEosinophiltIgETotal Immunoglobulin EsIgESpecific Immunoglobulin EMPMycoplasma pneumoniaeGINAthe Global Initiative for AsthmaIQRInterquartile RangeOROdds RatiosLOSLength of StayCIConfidence IntervalsRTIRespiratory Tract InfectionSABAShort Acting BronchodilatorICSInhaled CorticosteroidIUInternational UnitMLMilliliterIgMImmunoglobulin M.