Mathias Tremp1, Carlo M Oranges2, Martin Majewski3, Dirk J Schaefer2, Daniel F Kalbermatten2, Constantine Bloch-Infanger4, Peter E Ochsner3. 1. Department of Plastic, Reconstructive, Aesthetic, and Hand Surgery, Basel University Hospital, University of Basel, Basel, Switzerland Mathias.Tremp@usb.ch. 2. Department of Plastic, Reconstructive, Aesthetic, and Hand Surgery, Basel University Hospital, University of Basel, Basel, Switzerland. 3. Department of Orthopedic Surgery, Basel University Hospital, University of Basel, Basel, Switzerland. 4. Division of Infectious Diseases & Hospital Epidemiology, Basel University Hospital, University of Basel, Basel, Switzerland.
Abstract
BACKGROUND: Management of post-traumatic open fractures resulting from severe injuries of the lower extremity continues to challenge orthopedic and reconstructive surgeons. Moreover, post-traumatic osteoarticular infections due to Clostridium species are rare, with few reports in the literature. We describe possible pathomechanisms and propose treatment options for cases of delayed diagnosis of osteoarticular infections with Clostridium spp. CASE REPORTS: Two patients sustained severe osteoarticular infection due to Clostridium spp. after open epi- and metaphyseal fractures of the lower extremity. In combination with radical debridement, ankle arthrodesis and long-term antibiotic treatment, satisfactory results were achieved after a follow-up of 18 months and 24 years. CONCLUSION: Clostridium species are difficult to identify, treatment is usually delayed and most patients have unfavourable outcomes. Copyright
BACKGROUND: Management of post-traumatic open fractures resulting from severe injuries of the lower extremity continues to challenge orthopedic and reconstructive surgeons. Moreover, post-traumatic osteoarticular infections due to Clostridium species are rare, with few reports in the literature. We describe possible pathomechanisms and propose treatment options for cases of delayed diagnosis of osteoarticular infections with Clostridium spp. CASE REPORTS: Two patients sustained severe osteoarticular infection due to Clostridium spp. after open epi- and metaphyseal fractures of the lower extremity. In combination with radical debridement, ankle arthrodesis and long-term antibiotic treatment, satisfactory results were achieved after a follow-up of 18 months and 24 years. CONCLUSION: Clostridium species are difficult to identify, treatment is usually delayed and most patients have unfavourable outcomes. Copyright
Authors: Lars B Engesaeter; Stein Atle Lie; Birgitte Espehaug; Ove Furnes; Stein Emil Vollset; Leif Ivar Havelin Journal: Acta Orthop Scand Date: 2003-12
Authors: Carlo M Oranges; Mathias Tremp; Wenjin Wang; Srinivas Madduri; Pietro G DI Summa; Reto Wettstein; Dirk J Schaefer; Daniel F Kalbermatten Journal: In Vivo Date: 2018 May-Jun Impact factor: 2.155