Literature DB >> 31882241

Postoperative narcotic use in patients with ovarian cancer on an Enhanced Recovery After Surgery (ERAS) pathway.

Allison H Kay1, Monica Venn2, Renata Urban2, Heidi J Gray2, Barbara Goff2.   

Abstract

OBJECTIVES: To determine the impact of an ERAS pathway on post-discharge narcotic use for patients with ovarian cancer undergoing open surgery.
METHODS: This was a retrospective cohort study of women who underwent open ovarian cancer surgeries in 2014 prior to ERAS ("pre-ERAS") and in 2016/2018 after ERAS was instituted ("ERAS"). Patients taking chronic narcotics were excluded. A statewide prescription monitoring program was used to identify narcotic prescriptions filled in the three months after surgery. Quantity of narcotic medication is referenced in morphine milligram equivalents (MME).
RESULTS: 42 pre-ERAS and 94 ERAS patients were included. The groups were similar in age, BMI, diabetes, tobacco use, mean number of prior abdominal/pelvic surgeries, and advanced stage disease. ERAS patients had a shorter hospital stay (6.7 days pre-ERAS vs 4.2 days ERAS, p = 0.003), used less narcotic in the 24 h prior to discharge (74.0 MME pre-ERAS vs 25.8 MME ERAS, p = 0.002), and filled prescriptions at time of discharge for less narcotic (519.9 MME pre-ERAS vs 339.7 MME ERAS, p = 0.011). After hospital discharge, ERAS patients filled fewer additional prescriptions (52.4% pre-ERAS, vs 29.4% ERAS, p = 0.012). In total, ERAS patients filled prescriptions for 55% fewer narcotics in the three months after surgery than the pre-ERAS group (1101.4 MME pre-ERAS vs 492.1 MME ERAS, p < 0.001).
CONCLUSIONS: Institution of an ERAS protocol appears to decrease the narcotic needs of patients in the three months after ovarian cancer surgery.
Copyright © 2019 Elsevier Inc. All rights reserved.

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Year:  2019        PMID: 31882241     DOI: 10.1016/j.ygyno.2019.12.018

Source DB:  PubMed          Journal:  Gynecol Oncol        ISSN: 0090-8258            Impact factor:   5.482


  4 in total

1.  Risk factors of perioperative complications and management with enhanced recovery after primary surgery in women with epithelial ovarian carcinoma in a single center.

Authors:  Min Li; Tianjiao Zhang; Jing Zhu; Yuebo Li; Wenying Chen; Yanhu Xie; Wei Zhang; Rongzhu Chen; Wei Wei; Guihong Wang; Jiwei Qin; Weidong Zhao; Dabao Wu; Zhen Shen; Björn Nashan; Ying Zhou
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Review 2.  Perioperative enhanced recovery programmes for women with gynaecological cancers.

Authors:  Janita Pak Chun Chau; Xu Liu; Suzanne Hoi Shan Lo; Wai Tong Chien; Sze Ki Hui; Kai Chow Choi; Jie Zhao
Journal:  Cochrane Database Syst Rev       Date:  2022-03-15

3.  Role of sex hormones in modulating breast and ovarian cancer associated pain.

Authors:  Melissa C McHann; Henry L Blanton; Josée Guindon
Journal:  Mol Cell Endocrinol       Date:  2021-05-24       Impact factor: 4.369

4.  One shot to control Pain: Decreasing postoperative opioid use in gynecologic oncology patients with intrathecal opioid injection.

Authors:  Yevgeniya Ioffe; Ruofan Yao; Eileen Hou; Michelle Wheeler; Mohamed Nour; Wei Yun Wang; Linda Hong
Journal:  Gynecol Oncol Rep       Date:  2021-09-06
  4 in total

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