| Literature DB >> 31881801 |
Yun Kyu Kim1,2, Myeong Gu Yeo3, Bo Kang Oh2, Ha Yeong Kim2, Hun Ji Yang2, Seung-Sik Cho4, Minchan Gil1, Kyung Jin Lee2.
Abstract
We wish to make the following corrections to this paper [...].Entities:
Year: 2019 PMID: 31881801 PMCID: PMC6981832 DOI: 10.3390/ijms21010174
Source DB: PubMed Journal: Int J Mol Sci ISSN: 1422-0067 Impact factor: 5.923
Figure 1Effect of TS on survival and lung injury in cecal ligation and puncture (CLP)-induced septic mice. (A) To examine the effect of TS on the survival of CLP-induced septic mice, survival of mice was then monitored every 24 h for up to 8 days for the following experimental groups (a) sham control; mice were orally administered with either (b) vehicle (corn oil, 0.1 mL per mouse, n = 5), (c) 1 mg/kg TS (n = 5), or (d) 10 mg/kg TS (n = 5), 2 h prior to the operation. Significantly different from CLP-induced septic group (B) Expression of COX-2 and TNF-α transcripts in the isolated PAM were determined by real-time PCR; * p < 0.05 vs. CLP-induced septic group (n = 3 in each group) (C) The lungs from each experimental group were processed for histologic evaluation 1 day after CLP. Representative histologic changes in lung tissue obtained from mice belonging to each group are displayed and the arrows indicate the damaged area (hematoxylin and eosin staining; magnification 400×). Scale bar represents 200 um. (D) The extent of lung injury was estimated using scores in different sections for neutrophil infiltration, hemorrhage, necrosis, congestion, and edema. * p < 0.05 vs. CLP-induced septic group (n = 3 in each group).