Literature DB >> 31881233

Neuroprotective effect of metformin on dopaminergic neurodegeneration and α-synuclein aggregation in C. elegans model of Parkinson's disease.

Nada Saewanee1, Theethawat Praputpittaya1, Nawaphat Malaiwong2, Pawanrat Chalorak2, Krai Meemon3.   

Abstract

Entities:  

Keywords:  Caenorhabditis elegans; Dopaminergic neuron; Metformin; Neuroprotection; Parkinson’s Disease; α-Synuclein

Mesh：

Substances：

Year:  2019        PMID： 31881233     DOI： 10.1016/j.neures.2019.12.017

Source DB:  PubMed          Journal:  Neurosci Res        ISSN： 0168-0102            Impact factor:   3.304


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  11 in total

1.  Compounds that extend longevity are protective in neurodegenerative diseases and provide a novel treatment strategy for these devastating disorders.

Authors:  Sonja K Soo; Paige D Rudich; Annika Traa; Namasthée Harris-Gauthier; Hazel J Shields; Jeremy M Van Raamsdonk
Journal:  Mech Ageing Dev       Date:  2020-06-28       Impact factor: 5.432

2.  Metformin improves depressive-like behavior in experimental Parkinson's disease by inducing autophagy in the substantia nigra and hippocampus.

Authors:  Ingrid Prata Mendonça; Igor Henrique Rodrigues de Paiva; Eduardo Pereira Duarte-Silva; Michel Gomes de Melo; Rodrigo S da Silva; Maria Isabelly Xavier do Nascimento; Christina Alves Peixoto
Journal:  Inflammopharmacology       Date:  2022-08-06       Impact factor: 5.093

Review 3.  Modulation of Reactive Oxygen Species Homeostasis as a Pleiotropic Effect of Commonly Used Drugs.

Authors:  Carolin Thomas; Lia Wurzer; Ernst Malle; Michael Ristow; Corina T Madreiter-Sokolowski
Journal:  Front Aging       Date:  2022-06-14

Review 4.  Using Caenorhabditis elegans to Model Therapeutic Interventions of Neurodegenerative Diseases Targeting Microbe-Host Interactions.

Authors:  Chenyin Wang; Chaogu Zheng
Journal:  Front Pharmacol       Date:  2022-04-28       Impact factor: 5.988

Review 5.  Exploring the Pharmacological Potential of Metformin for Neurodegenerative Diseases.

Authors:  Ming-Rui Du; Quan-You Gao; Chen-Lin Liu; Lin-Ya Bai; Tian Li; Fei-Long Wei
Journal:  Front Aging Neurosci       Date:  2022-04-26       Impact factor: 5.702

6.  Metformin as a Potential Neuroprotective Agent in Prodromal Parkinson's Disease-Viewpoint.

Authors:  Carolina Sportelli; Daniele Urso; Peter Jenner; K Ray Chaudhuri
Journal:  Front Neurol       Date:  2020-06-12       Impact factor: 4.003

7.  Identification of hub genes and small-molecule compounds in medulloblastoma by integrated bioinformatic analyses.

Authors:  Zhendong Liu; Ruotian Zhang; Zhenying Sun; Jiawei Yao; Penglei Yao; Xin Chen; Xinzhuang Wang; Ming Gao; Jinzhao Wan; Yiming Du; Shiguang Zhao
Journal:  PeerJ       Date:  2020-04-14       Impact factor: 2.984

Review 8.  Metformin Repurposing for Parkinson Disease Therapy: Opportunities and Challenges.

Authors:  Francesco Agostini; Anna Masato; Luigi Bubacco; Marco Bisaglia
Journal:  Int J Mol Sci       Date:  2021-12-30       Impact factor: 5.923

9.  Ferulic Acid Exerts Neuroprotective Effects via Autophagy Induction in C. elegans and Cellular Models of Parkinson's Disease.

Authors:  Tao Long; Qian Wu; Jing Wei; Yong Tang; Yan-Ni He; Chang-Long He; Xue Chen; Lu Yu; Chong-Lin Yu; Betty Yuen-Kwan Law; Jian-Ming Wu; Da-Lian Qin; An-Guo Wu; Xiao-Gang Zhou
Journal:  Oxid Med Cell Longev       Date:  2022-02-22       Impact factor: 6.543

Review 10.  Recent Neurotherapeutic Strategies to Promote Healthy Brain Aging: Are we there yet?

Authors:  Chul-Kyu Kim; Perminder S Sachdev; Nady Braidy
Journal:  Aging Dis       Date:  2022-02-01       Impact factor: 6.745
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