| Literature DB >> 31880668 |
Rachel E Harris1, Hazel Duncan1, Elaine Buchanan1, Tracey Cardigan1, Vikki Garrick1, Lee Curtis1, Lisa Gervais1, Andrew Barclay1, Graham Haddock2, Richard Hansen1, Rachel Tayler1, Gregor Walker2, Richard K Russell1.
Abstract
Exclusive enteral nutrition (EEN) is effective in inducing remission in paediatric Crohn Disease (CD) and has been shown to reduce inflammation and improve outcomes in adult CD patients when used before resectional surgery. This retrospective study demonstrates that preoperative EEN is achievable in paediatric CD patients undergoing right hemicolectomy and is associated with positive peri-operative outcomes. Seventeen patients (8 who received preoperative EEN and 9 who did not) were included in the study. Six of 8 (75.0%) managed EEN orally; 1 via nasogastric tube and another via a previously sited gastrostomy. Use of preoperative EEN was associated with a decreased rate of moderate/severe disease on resection pathology (5/8 [62.5%] vs 9/9 [100%]; P = 0.04). Larger studies are required to determine the wider potential benefits of preoperative EEN on postoperative outcomes within paediatric practice.Entities:
Mesh:
Year: 2020 PMID: 31880668 DOI: 10.1097/MPG.0000000000002595
Source DB: PubMed Journal: J Pediatr Gastroenterol Nutr ISSN: 0277-2116 Impact factor: 2.839