Literature DB >> 31879500

Augmented debridement for implant related chronic osteomyelitis with an absorbable, gentamycin loaded calcium sulfate/hydroxyapatite biocomposite.

Efstathios Drampalos1, Hasan Raza Mohammad1, Anand Pillai1.   

Abstract

We report outcomes from 52 patients with chronic osteomyelitis from implant infection treated with a single stage protocol including debridement augmented with application of CERAMENT™/G biocomposite after resection of Cierny-Mader (C-M) stage III and IV chronic osteomyelitis. Mean age was 53 years with a mean follow up of 17 months. Infection was eradicated in 48 (92.3%) patients. There were four (7.7%) recurrences. Eighteen patients (35%) had a flap. Staphylococci (51%) and Enterococci (15%) were the commonest microorganisms. Local antibiotic augmentation (CERAMENT™/G biocomposite) with dead space management is effective in the treatment of implant related chronic osteomyelitis. LEVEL OF EVIDENCE: Prognostic Level IV. Crown
Copyright © 2019 Published by Elsevier B.V. on behalf of Professor P K Surendran Memorial Education Foundation. All rights reserved.

Entities:  

Keywords:  Absorbable; Augmented debridement; Gentamycin loaded calcium sulphate/hydroxyapatite biocomposite; Implant related osteomyelitis

Year:  2019        PMID： 31879500      PMCID： PMC6919360          DOI： 10.1016/j.jor.2019.08.017

Source DB:  PubMed          Journal:  J Orthop        ISSN： 0972-978X


  13 in total

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Authors:  Riccardo Iundusi; Elena Gasbarra; Michele D'Arienzo; Andrea Piccioli; Umberto Tarantino
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  7 in total

1.  Application of vancomycin-impregnated calcium sulfate hemihydrate/nanohydroxyapatite/carboxymethyl chitosan injectable hydrogels combined with BMSC sheets for the treatment of infected bone defects in a rabbit model.

Authors:  Yanjun Wang; Zihou Zhao; Shiyu Liu; Wen Luo; Guoliang Wang; Zhenfeng Zhu; Qiong Ma; Yunyan Liu; Linhu Wang; Shuaikun Lu; Yong Zhang; Jixian Qian; Yunfei Zhang
Journal:  BMC Musculoskelet Disord       Date:  2022-06-09       Impact factor: 2.562

2.  In Vitro Evaluation of Gentamicin or Vancomycin Containing Bone Graft Substitute in the Prevention of Orthopedic Implant-Related Infections.

Authors:  Alessandro Bidossi; Marta Bottagisio; Nicola Logoluso; Elena De Vecchi
Journal:  Int J Mol Sci       Date:  2020-12-04       Impact factor: 5.923

3.  Transglutaminase Cross-Linked Gelatin-Alginate-Antibacterial Hydrogel as the Drug Delivery-Coatings for Implant-Related Infections.

Authors:  Chung-Kai Sun; Cherng-Jyh Ke; Yi-Wen Lin; Feng-Huei Lin; Tung-Hu Tsai; Jui-Sheng Sun
Journal:  Polymers (Basel)       Date:  2021-01-28       Impact factor: 4.329

4.  Antibiotic-loaded calcium sulfate beads in spinal surgery for patients with spondylodiscitis: a clinical retrospective study.

Authors:  Xiaojie Tang; Jianyi Li; Chunxiao Wang; Fang Liu; Jianwei Guo; Jiangwei Tan; Qinyong Song; Haifei Cao; Yao Zhang
Journal:  BMC Musculoskelet Disord       Date:  2022-03-19       Impact factor: 2.362

5.  Combined Orthoplastic Approach in Fracture-Related Infections of the Distal Tibia.

Authors:  Andrea Sambri; Marco Pignatti; Sara Tedeschi; Maria Elisa Lozano Miralles; Claudio Giannini; Michele Fiore; Matteo Filippini; Riccardo Cipriani; Pierluigi Viale; Massimiliano De Paolis
Journal:  Microorganisms       Date:  2022-08-12

6.  Gastrocnemius muscle flap with vancomycin/gentamicin-calcium sulfate and autogenous iliac bone graft for the phase I treatment of localized osteomyelitis after tibial plateau fracture surgery.

Authors:  Weiwei Ruan; Menglu Li; Qiaofeng Guo; Bingyuan Lin
Journal:  J Orthop Surg Res       Date:  2021-05-27       Impact factor: 2.359

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Authors:  Eva Steinhausen; Rolf Lefering; Martin Glombitza; Nikolaus Brinkmann; Carsten Vogel; Bastian Mester; Marcel Dudda
Journal:  J Bone Jt Infect       Date:  2021-05-27
  7 in total

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