Literature DB >> 31879490

End-capping of amputation stumps with a local antibiotic containing hydroxyapatite bio-composite - A report of 13 cases with chronic lower limb osteomyelitis.

Anoop Anugraha1, Noman Jehangir1, Mohammed Alqubaisi1, Asan Rafee2, Nasser Kurdy1, Anand Pillai1.   

Abstract

We present our novel technique of end capping of amputation stumps with absorbable antibiotic containing hydroxyapatite bone cement as a marrow plug controlling bleeding and achieving high local concentration of antibiotics in cases complicated by chronic osteomyelitis.Our case series consisted of 13 patients who underwent lower limb amputations for chronic medullary osteomyelitis.Of 13 patients 12 had below knee and 1 had above knee amputation. All wounds healed uneventfully without any surgical site infection. There were no stump hematomas/seromas or instances of recurrent stump osteomyelitis or need for revision surgery.
© 2019 Professor P K Surendran Memorial Education Foundation. Published by Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Amputation stumps; Cerament; Chronic osteomyelitis; Endcapping; Stump revision

Year:  2019        PMID: 31879490      PMCID: PMC6919344          DOI: 10.1016/j.jor.2019.11.007

Source DB:  PubMed          Journal:  J Orthop        ISSN: 0972-978X


  12 in total

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9.  Fluid collections in amputations are not indicative or predictive of infection.

Authors:  Elizabeth M Polfer; Benjamin W Hoyt; Lien T Senchak; Mark D Murphey; Jonathan A Forsberg; Benjamin K Potter
Journal:  Clin Orthop Relat Res       Date:  2014-10       Impact factor: 4.176

10.  Pharmacokinetics of gentamicin eluted from a regenerating bone graft substitute: In vitro and clinical release studies.

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  1 in total

Review 1.  Management of bone diseases: looking at scaffold-based strategies for drug delivery.

Authors:  Myriam Bordone; Ana Bettencourt
Journal:  Drug Deliv Transl Res       Date:  2022-07-11       Impact factor: 5.671

  1 in total

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