Literature DB >> 31873726

An expert opinion paper on statin adherence and implementation of new lipid-lowering medications by the ESC Working Group on Cardiovascular Pharmacotherapy: Barriers to be overcome.

Heinz Drexel1,2,3,4, Andrew J S Coats5,6, Ilaria Spoletini7, Claudio Bilato8, Vincenzo Mollace9, Pasquale Perrone Filardi10, Giuseppe M C Rosano7.   

Abstract

Benefits and safety on statins have been well-established over 20 years of research. Despite this, the vast majority of patients are not adequately treated and do not achieve the low-density lipoprotein cholesterol target levels. This is mainly due to poor adherence, which is associated with dangerous and sometimes fatal outcomes. To increase adherence and prevent worse outcomes, a combination therapy with lower dosage of statins and new lipid-lowering drugs may be used. However, the implementation of new lipid-lowering drugs in European countries is still at the beginning. For these reasons, the aim of this position paper is to give an up-to-date indication from the ESC Working Group on Cardiovascular Pharmacotherapy in order to discuss the barriers towards statins adherence and new lipid-lowering drugs implementation in Europe. Published on behalf of the European Society of Cardiology. All rights reserved.
© The Author(s) 2019. For permissions, please email: journals.permissions@oup.com.

Entities:  

Keywords:  Ezetimibe; Low-density lipoprotein cholesterol; PCSK9 inhibitors; Position paper; Statin intolerance; Statins adherence

Mesh:

Substances:

Year:  2020        PMID: 31873726     DOI: 10.1093/ehjcvp/pvz079

Source DB:  PubMed          Journal:  Eur Heart J Cardiovasc Pharmacother


  11 in total

1.  Lipid therapy: A new whiteboard video for patient education.

Authors:  Margaret L Ackman; Sheri Koshman; Glen J Pearson; William Semchuk; Yana Shamiss; Ann Thompson; Travis Warner
Journal:  Can Pharm J (Ott)       Date:  2021-04-23

2.  Asymptomatic Left Ventricular Hypertrophy Is a Potent Risk Factor for the Development of HFpEF but Not HFrEF: Results of a Retrospective Cohort Study.

Authors:  Artem Ovchinnikov; Evgeny Belyavskiy; Alexandra Potekhina; Fail Ageev
Journal:  J Clin Med       Date:  2022-07-04       Impact factor: 4.964

3.  The beneficial effect over 3 years by pictorial information to patients and their physician about subclinical atherosclerosis and cardiovascular risk: Results from the VIPVIZA randomized clinical trial.

Authors:  Anna Bengtsson; Margareta Norberg; Nawi Ng; Bo Carlberg; Christer Grönlund; Johan Hultdin; Bernt Lindahl; Bertil Lindahl; Steven Nordin; Emma Nyman; Patrik Wennberg; Per Wester; Ulf Näslund
Journal:  Am J Prev Cardiol       Date:  2021-05-21

Review 4.  Is it Time for Single-Pill Combinations in Dyslipidemia?

Authors:  François Schiele; Leopoldo Pérez de Isla; Marcello Arca; Charalambos Vlachopoulos
Journal:  Am J Cardiovasc Drugs       Date:  2021-09-22       Impact factor: 3.283

Review 5.  Current Perspectives on the Attainment of Lipid Modification Goals Relating to the Use of Statins and Ezetimibe for the Prevention of Cardiovascular Disease in the United Kingdom.

Authors:  Timothy Mark Reynolds; Alison Pottle; Sadat H Quoraishi
Journal:  Vasc Health Risk Manag       Date:  2021-05-21

6.  Adherence to Lipid-Lowering Treatment by Single-Pill Combination of Statin and Ezetimibe.

Authors:  Federico Rea; Laura Savaré; Giovanni Corrao; Giuseppe Mancia
Journal:  Adv Ther       Date:  2021-09-03       Impact factor: 3.845

7.  Effects of Xinjiang wild cherry plum (Prunus divaricata Ledeb) anthocyanin-rich extract on the plasma metabolome of atherosclerotic apoE-deficient mice fed a high-fat diet.

Authors:  Jing Shen; Xing Li; Xin Zhang; Zhen Li; Gulisitan Abulaiti; Yang Liu; Jun Yao; Pei Zhang
Journal:  Front Nutr       Date:  2022-07-25

8.  Effects of Alirocumab on Triglyceride Metabolism: A Fat-Tolerance Test and Nuclear Magnetic Resonance Spectroscopy Study.

Authors:  Thomas Metzner; Deborah R Leitner; Karin Mellitzer; Andrea Beck; Harald Sourij; Tatjana Stojakovic; Gernot Reishofer; Winfried März; Ulf Landmesser; Hubert Scharnagl; Hermann Toplak; Günther Silbernagel
Journal:  Biomedicines       Date:  2022-01-17

9.  Diabetic foot ulcers: Retrospective comparative analysis from Sicily between two eras.

Authors:  Valentina Guarnotta; Stefano Radellini; Enrica Vigneri; Achille Cernigliaro; Felicia Pantò; Salvatore Scondotto; Piero Luigi Almasio; Giovanni Guercio; Carla Giordano
Journal:  PLoS One       Date:  2021-12-07       Impact factor: 3.240

10.  Comparative Effect of Bergamot Polyphenolic Fraction and Red Yeast Rice Extract in Rats Fed a Hyperlipidemic Diet: Role of Antioxidant Properties and PCSK9 Expression.

Authors:  Rocco Mollace; Roberta Macrì; Annamaria Tavernese; Micaela Gliozzi; Vincenzo Musolino; Cristina Carresi; Jessica Maiuolo; Massimo Fini; Maurizio Volterrani; Vincenzo Mollace
Journal:  Nutrients       Date:  2022-01-22       Impact factor: 5.717

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