| Literature DB >> 31873726 |
Heinz Drexel1,2,3,4, Andrew J S Coats5,6, Ilaria Spoletini7, Claudio Bilato8, Vincenzo Mollace9, Pasquale Perrone Filardi10, Giuseppe M C Rosano7.
Abstract
Benefits and safety on statins have been well-established over 20 years of research. Despite this, the vast majority of patients are not adequately treated and do not achieve the low-density lipoprotein cholesterol target levels. This is mainly due to poor adherence, which is associated with dangerous and sometimes fatal outcomes. To increase adherence and prevent worse outcomes, a combination therapy with lower dosage of statins and new lipid-lowering drugs may be used. However, the implementation of new lipid-lowering drugs in European countries is still at the beginning. For these reasons, the aim of this position paper is to give an up-to-date indication from the ESC Working Group on Cardiovascular Pharmacotherapy in order to discuss the barriers towards statins adherence and new lipid-lowering drugs implementation in Europe. Published on behalf of the European Society of Cardiology. All rights reserved.Entities:
Keywords: Ezetimibe; Low-density lipoprotein cholesterol; PCSK9 inhibitors; Position paper; Statin intolerance; Statins adherence
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Year: 2020 PMID: 31873726 DOI: 10.1093/ehjcvp/pvz079
Source DB: PubMed Journal: Eur Heart J Cardiovasc Pharmacother