C Caburet1, N Farigon2, A Mulliez3, T Mom1, Y Boirie2, L Gilain1, N Saroul4. 1. Service d'ORL et Chirurgie Cervico-Faciale, CHU de Clermont-Ferrand, 58, rue Montalembert, 63000 Clermont-Ferrand, France. 2. Service de Nutrition Clinique, CHU de Clermont-Ferrand, 58, rue Montalembert, 63000 Clermont-Ferrand, France. 3. Service de la Recherche Clinique et de l'Innovation, Unité de Statistiques, 58, rue Montalembert, 63000 Clermont-Ferrand, France. 4. Service d'ORL et Chirurgie Cervico-Faciale, CHU de Clermont-Ferrand, 58, rue Montalembert, 63000 Clermont-Ferrand, France. Electronic address: nsaroul@chu-clermontferrand.fr.
Abstract
OBJECTIVES: Half of the patients presenting with head and neck tumor are malnourished at the outset of treatment. Muscle mass loss (sarcopenia) seems to be critical. The aim of the present study was to assess the impact of nutritional status and sarcopenia on postoperative complications in head and neck cancer. MATERIALS AND METHODS: A retrospective study for the period November 2014 to May 2016 included 92 patients operated on for head and neck squamous cell carcinoma. Complications at 30 days were graded on the 5-level Clavien-Dindo classification. Nutritional status was assessed anthropometrically (weight), biologically (albuminemia and Nutrition Risk Index (NRI)), on CT (muscle mass index at 3rd lumbar vertebra) and functionally (Short Physical Performance Battery). Assessment was made at the outset of management, and nutritional treatment was initiated as appropriate. Potential risk factors for postoperative complications were assessed: performance status, prior radiation therapy, smoking and alcohol abuse. RESULTS: 54% of patients were malnourished on the NRI. 41% had grade≥2 complications. The most frequent complications were infection and healing disorder. The risk of complications was higher in case of malnutrition (62% vs. 17%; P<0.001) and sarcopenia (56% vs. 22%; P<0.01), with 50% longer hospital stay (P=0.04). CONCLUSION: Malnutrition and sarcopenia are independent risk factors for postoperative complications.
OBJECTIVES: Half of the patients presenting with head and neck tumor are malnourished at the outset of treatment. Muscle mass loss (sarcopenia) seems to be critical. The aim of the present study was to assess the impact of nutritional status and sarcopenia on postoperative complications in head and neck cancer. MATERIALS AND METHODS: A retrospective study for the period November 2014 to May 2016 included 92 patients operated on for head and neck squamous cell carcinoma. Complications at 30 days were graded on the 5-level Clavien-Dindo classification. Nutritional status was assessed anthropometrically (weight), biologically (albuminemia and Nutrition Risk Index (NRI)), on CT (muscle mass index at 3rd lumbar vertebra) and functionally (Short Physical Performance Battery). Assessment was made at the outset of management, and nutritional treatment was initiated as appropriate. Potential risk factors for postoperative complications were assessed: performance status, prior radiation therapy, smoking and alcohol abuse. RESULTS: 54% of patients were malnourished on the NRI. 41% had grade≥2 complications. The most frequent complications were infection and healing disorder. The risk of complications was higher in case of malnutrition (62% vs. 17%; P<0.001) and sarcopenia (56% vs. 22%; P<0.01), with 50% longer hospital stay (P=0.04). CONCLUSION:Malnutrition and sarcopenia are independent risk factors for postoperative complications.
Authors: Kayla A Fay; Matthew E Maeder; Jennifer A Emond; Rian M Hasson; Timothy M Millington; David J Finley; Joseph D Phillips Journal: J Thorac Dis Date: 2022-06 Impact factor: 3.005
Authors: Bianca Tabita Muresan; Martín Núñez-Abad; Ana Artero; Jaime Rios Rios; Alberto Jacobo Cunquero-Tomás; Vega Iranzo; Javier Garrido; Ana Jiménez-Portilla; Carlos Camps Herrero; Carlos J Sánchez Juan Journal: J Nutr Metab Date: 2022-08-16