Literature DB >> 31867081

68Ga-PSMA: a One-stop Shop in Radioactive Iodine Refractory Thyroid Cancer?

Thabo Lengana1, Ismaheel O Lawal1, Kgomotso Mokoala1, Mariza Vorster1, Mike M Sathekge1.   

Abstract

We report a case of a 47-year-old female known with metastatic papillary thyroid cancer. Her treatment history included total thyroidectomy and 3 previous radio ablations with a cumulative dose of 950 mCi of 131I. On follow-up, her thyroglobulin levels had demonstrated a rising trend (from 3789.0 to 4240.0 ug/L) despite a 123I whole-body scan demonstrating a reduction in tracer avid lesions. She was suspected of having radio-resistant disease. The patient underwent both 18F-FDG and 68Ga-PSMA PET/CT imaging with both scans demonstrating congruent lesions however with far greater intensity on the 68Ga-PSMA study. © Korean Society of Nuclear Medicine 2019.

Entities:  

Keywords:  18F-FDG; 68Ga-PSMA; Radioactive iodine refractory thyroid; Thyroid cancer

Year:  2019        PMID: 31867081      PMCID: PMC6898693          DOI: 10.1007/s13139-019-00621-x

Source DB:  PubMed          Journal:  Nucl Med Mol Imaging        ISSN: 1869-3474


  11 in total

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7.  Prognostic significance of FDG PET/CT on the follow-up of patients of differentiated thyroid carcinoma with negative 131I whole-body scan and elevated thyroglobulin levels: correlation with clinical and histopathologic characteristics and long-term follow-up data.

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8.  Fluorine-18-FDG and iodine-131-iodide uptake in thyroid cancer.

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10.  68Ga-PSMA-HBED-CC PET imaging in breast carcinoma patients.

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Review 1.  PSMA radioligand therapy for solid tumors other than prostate cancer: background, opportunities, challenges, and first clinical reports.

Authors:  M J M Uijen; Y H W Derks; W A M van Gemert; J Nagarajah; R I J Merkx; M G M Schilham; J Roosen; B M Privé; S A M van Lith; C M L van Herpen; M Gotthardt; S Heskamp
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