| Literature DB >> 31866291 |
Abstract
Advances in molecular biology, optics, genetics, and bioinformatics have opened the door to mapping, in molecular detail, processes inside living cells. With the ability to observe the individual moving parts of cellular machinery, concepts formerly confined to physics are entering mainstream biology. This article discusses a few ideas of this sort related to chromosome biology, to illustrate what kinds of insights physics might yet bring to our understanding of living systems.Entities:
Keywords: chromatin; chromosomes; phase separation; polymer biophysics; quantitative biology
Mesh:
Year: 2019 PMID: 31866291 PMCID: PMC6948178 DOI: 10.1016/j.jmb.2019.11.022
Source DB: PubMed Journal: J Mol Biol ISSN: 0022-2836 Impact factor: 5.469