Literature DB >> 318653

Number of mutations required to evolve a new lactase function in Escherichia coli.

B G Hall.   

Abstract

The frequency of mutation of the ebgAo allele to ebgA+ was compared with the frequency of mutation of strA+ to strA-. The observation that both spontaneous and ethyl methane sulfonate-induced mutations to ebgA+ occurred more frequently than mutations to strA- suggests that ebgA+ mutants arise as the result of single-point mutations.

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Year:  1977        PMID： 318653      PMCID： PMC234956          DOI： 10.1128/jb.129.1.540-543.1977

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  8 in total

1.  Regulation of newly evolved enzymes. II. The ebg repressor.

Authors:  B G Gall; D L Hartl
Journal:  Genetics       Date:  1975-11       Impact factor: 4.562

2.  Mutations of Bacteria from Virus Sensitivity to Virus Resistance.

Authors:  S E Luria; M Delbrück
Journal:  Genetics       Date:  1943-11       Impact factor: 4.562

Review 3.  Recalibrated linkage map of Escherichia coli K-12.

Authors:  B J Bachmann; K B Low; A L Taylor
Journal:  Bacteriol Rev       Date:  1976-03

4.  Second naturally occurring beta-galactosidase in E. coli.

Authors:  D L Hartl; B G Hall
Journal:  Nature       Date:  1974-03-08       Impact factor: 49.962

5.  Mutagenic topography of the E. coli chromosome.

Authors:  J van Brunt; G Edlin
Journal:  J Mol Evol       Date:  1975-09-08       Impact factor: 2.395

6.  Evolution of a second gene for beta-galactosidase in Escherichia coli.

Authors:  J H Campbell; J A Lengyel; J Langridge
Journal:  Proc Natl Acad Sci U S A       Date:  1973-06       Impact factor: 11.205

7.  Lactose-utilizing mutants of lac deletion strains of Escherichia coli.

Authors:  R A Warren
Journal:  Can J Microbiol       Date:  1972-09       Impact factor: 2.419

8.  Regulation of newly evolved enzymes. I. Selection of a novel lactase regulated by lactose in Escherichia coli.

Authors:  B G Hall; D L Hartl
Journal:  Genetics       Date:  1974-03       Impact factor: 4.562
  8 in total
  5 in total

1.  A third beta-galactosidase in a strain of Klebsiella that possesses two lac genes.

Authors:  B G Hall; E C Reeve
Journal:  J Bacteriol       Date:  1977-10       Impact factor: 3.490

2.  Topological repression of gene activity by a transposable element.

Authors:  H W Stokes; B G Hall
Journal:  Proc Natl Acad Sci U S A       Date:  1984-10       Impact factor: 11.205

3.  The ebg operon consists of at least two genes.

Authors:  B G Hall; T Zuzel
Journal:  J Bacteriol       Date:  1980-12       Impact factor: 3.490

4.  Evolution of a new enzymatic function by recombination within a gene.

Authors:  B G Hall; T Zuzel
Journal:  Proc Natl Acad Sci U S A       Date:  1980-06       Impact factor: 11.205

5.  DNA sequence analysis of artificially evolved ebg enzyme and ebg repressor genes.

Authors:  B G Hall; P W Betts; J C Wootton
Journal:  Genetics       Date:  1989-12       Impact factor: 4.562
  5 in total

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