Literature DB >> 31864

Regulation of monkey liver serine hydroxymethyltransferase by nicotinamide nucleotide.

K S Ramesh, N A Rao.   

Abstract

The positive homotropic binding of tetrahydrofolate to monkey liver serine hydroxymethyltransferase was abolished on preincubating the enzyme with NADH and NADPH. NAD+ was a negative heterotropic effector, whereas NADP+ was without effect. The allosteric effects of nicotinamide nucleotides on the serine hydroxymethyltransferase, reported for the first time, lead to a better understanding of the regulation of the metabolic interconversion of folate coenzymes.

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Year:  1978        PMID： 31864      PMCID： PMC1186011          DOI： 10.1042/bj1741055

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  14 in total

1.  Distribution of folic acid derivatives in natural material. I. Chicken liver folates.

Authors:  J M NORONHA; M SILVERMAN
Journal:  J Biol Chem       Date:  1962-10       Impact factor: 5.157

2.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

3.  Purification and characterization of pyridoxal 5'-phosphate dependent serine hydroxymethylase from lamb liver and its action upon beta-phenylserines.

Authors:  R J Ulevitch; R G Kallen
Journal:  Biochemistry       Date:  1977-11-29       Impact factor: 3.162

4.  Mammalian methylenetetrahydrofolate reductase. Partial purification, properties, and inhibition by S-adenosylmethionine.

Authors:  C Kutzbach; E L Stokstad
Journal:  Biochim Biophys Acta       Date:  1971-12-15

5.  Identification of folic acid compounds in rat liver.

Authors:  Y S Shin; M A Williams; E L Stokstad
Journal:  Biochem Biophys Res Commun       Date:  1972-04-14       Impact factor: 3.575

6.  Stereochemistry of methylene transfer involving 5,10-methylenetetrahydrofolate.

Authors:  C M Tatum; P A Benkovic; S J Benkovic; R Potts; E Schleicher; H G Floss
Journal:  Biochemistry       Date:  1977-03-22       Impact factor: 3.162

7.  Serine transhydroxymethylase: evidence for a sequential random mechanism.

Authors:  L V Schirch; C M Tatum; S J Benkovic
Journal:  Biochemistry       Date:  1977-02-08       Impact factor: 3.162

8.  Mechanistic, inhibitory and stereochemical studies on cytoplasmic and mitochondrial serine transhydorxymethylases.

Authors:  M Akhtar; H A El-Obeid; P M Jordan
Journal:  Biochem J       Date:  1975-02       Impact factor: 3.857

9.  The regulation of folate and methionine metabolism.

Authors:  H A Krebs; R Hems; B Tyler
Journal:  Biochem J       Date:  1976-08-15       Impact factor: 3.857

10.  Cooperative interactions of tetrahydrofolate with purified pig kidney serine transhydroxymethylase and loss of this cooperativity in L1210 tumors and in tissues of mice bearing these tumors.

Authors:  P M Kumar; J A North; J H Mangum; N A Rao
Journal:  Proc Natl Acad Sci U S A       Date:  1976-06       Impact factor: 11.205
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  3 in total

1.  Serine hydroxymethyltransferase from soybean root nodules : purification and kinetic properties.

Authors:  M K Mitchell; P H Reynolds; D G Blevins
Journal:  Plant Physiol       Date:  1986-06       Impact factor: 8.340

2.  Inhibition of monkey liver serine hydroxymethyltransferase by Cibacron Blue 3G-A.

Authors:  K S Ramesh; N Appaji Rao
Journal:  Biochem J       Date:  1980-04-01       Impact factor: 3.857

3.  Purification and physicochemical, kinetic and immunological properties of allosteric serine hydroxymethyltransferase from monkey liver.

Authors:  K S Ramesh; N Appaji Rao
Journal:  Biochem J       Date:  1980-06-01       Impact factor: 3.857
  3 in total

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