| Literature DB >> 31861247 |
Takanori Kanazawa1,2, Takumi Kurano1,2, Hisako Ibaraki1, Yuuki Takashima1, Toyofumi Suzuki2, Yasuo Seta1.
Abstract
The appropriate information for the reprint used with permission from [...].Entities:
Year: 2019 PMID: 31861247 PMCID: PMC6956310 DOI: 10.3390/pharmaceutics11120689
Source DB: PubMed Journal: Pharmaceutics ISSN: 1999-4923 Impact factor: 6.321
Figure 2Cellular uptake of siRNA and cytotoxicity by PEG-PCL-Tat micelles in rat RN33B neuronal cells. RN33B cells were transfected with naked FAM-siRNA (1 μg), FAM-siRNA (1 μg) complexed with PEG-PCL-Tat (N/P ratio: 5–30), or Lipotrust as positive control. (A) After incubation for 4 h, the cellular uptake (%) of FAM-siRNA into RN33B cells was determined by flow cytometry. (B) Adapted with permission from [2]. Copyright 2019 American Chemical Society. After incubation for 3 h, in vitro cytotoxicity by PEG-PCL-Tat was determined by WST-8 assay. Each bar represents the mean ± S.D. (n = 4). **p < 0.01 vs. other groups, n.s.p > 0.05.