Literature DB >> 31859931

IS SUPERFICIAL COLORECTAL LESIONS WITH LOW AND HIGH GRADES INTRAEPITHELIAL NEOPLASMS MORE PREVALENT IN OLDER ABOVE 65 YEARS?

Nildete Rodrigues Diger1,2, Luiz Fernando Kubrusly1, Paulo Afonso Nunes Nassif1, Artur Adolfo Parada1,2, Giovana Tonello Bolsi1, Harymy Costa Barros Teixeira1, Osvaldo Malafaia1.   

Abstract

BACKGROUND: Colorectal cancer has a higher incidence in the rectum and sigmoid. However, with the expansion of the diagnosis of superficial lesions interest in the diagnosis and in the role they play in colorectal carcinogenesis has increased. AIM: To verify the behavior of superficial lesions of the colon and rectum, comparing the pathological and endoscopic findings, below and above 65 years.
METHODS: Cross-sectional study with prospective evaluation of standard protocol, where 200 patients with colorectal superficial lesions were evaluated; they were submitted to colonoscopy and mucosectomy of these lesions. They were divided in two age groups, below and above 65 years.
RESULTS: One hundred-and-eight were women (54%) and 92 men (46%). Most colon lesions were localized in the right colon (95%) and the remaining (5%) in the rectum. In endoscopy, 77.20% were granular lesions in patients under 65 years and 77.90% above. Colon histology showed low grade intraepithelial neoplasia, being 69.79% in patients under and 73.70% in above 65 years. In rectum, above 65 years the incidence of high-grade intraepithelial neoplasia was higher (66.70%).
CONCLUSION: The superficial colorectal lesions have been more endoscopically diagnosed today, and the highest incidence is the granular type, both in the colon and rectum, regardless of age. Regardless the age, histologically colon lesions were more as low grade intraepithelial neoplasia. In rectum, there was distinction for both age groups, being more frequent high grade intraepithelial neoplasia in patients over 65 years.

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Year:  2019        PMID: 31859931      PMCID: PMC6918745          DOI: 10.1590/0102-672020190001e1478

Source DB:  PubMed          Journal:  Arq Bras Cir Dig        ISSN: 0102-6720


  20 in total

1.  Endoscopic indications for endoscopic mucosal resection of laterally spreading tumours in the colorectum.

Authors:  T Uraoka; Y Saito; T Matsuda; H Ikehara; T Gotoda; D Saito; T Fujii
Journal:  Gut       Date:  2006-05-08       Impact factor: 23.059

2.  The Cooperative Italian FLIN Study Group: prevalence and clinico-pathological features of colorectal laterally spreading tumors.

Authors:  G Rotondano; M A Bianco; F Buffoli; G Gizzi; F Tessari; L Cipolletta
Journal:  Endoscopy       Date:  2011-08-08       Impact factor: 10.093

3.  Clinicopathological differences of laterally spreading tumors of the colorectum according to gross appearance.

Authors:  B C Kim; H J Chang; K Su Han; D K Sohn; C W Hong; J W Park; S-C Park; H S Choi; J H Oh
Journal:  Endoscopy       Date:  2010-12-16       Impact factor: 10.093

4.  [Clinicopathologic evaluation on colorectal laterally spreading tumor (LST)].

Authors:  T Okamoto; S Tanaka; K Haruma; Y Hiraga; M Kunihiro; H Goishi; T Tanimoto; M Sumii; M Yoshihara; K Sumii; G Kajiyama; F Shimamoto
Journal:  Nihon Shokakibyo Gakkai Zasshi       Date:  1996-02

5.  Gastrointestinal epithelial neoplasia: Vienna revisited.

Authors:  M F Dixon
Journal:  Gut       Date:  2002-07       Impact factor: 23.059

6.  Colonoscopic resection of lateral spreading tumours: a prospective analysis of endoscopic mucosal resection.

Authors:  D P Hurlstone; D S Sanders; S S Cross; I Adam; A J Shorthouse; S Brown; K Drew; A J Lobo
Journal:  Gut       Date:  2004-09       Impact factor: 23.059

7.  Histological Distinction between the Granular and Nongranular Types of Laterally Spreading Tumors of the Colorectum.

Authors:  Shingo P Goto; Naoto Sakamoto; Hiroyuki Mitomi; Takashi Murakami; Hideaki Ritsuno; Hiroya Ueyama; Kenshi Matsumoto; Tomoyoshi Shibuya; Taro Osada; Akihito Nagahara; Tatsuo Ogihara; Takashi Yao; Sumio Watanabe
Journal:  Gastroenterol Res Pract       Date:  2014-08-11       Impact factor: 2.260

Review 8.  PRE- AND POSTOPERATIVE IMAGING METHODS IN COLORECTAL CANCER.

Authors:  Gleim Dias de Souza; Luciana Rodrigues Queiroz Souza; Ronaldo Mafia Cuenca; Vinícius Martins Vilela; Bruno Eduardo de Morais Santos; Felipe Souza de Aguiar
Journal:  Arq Bras Cir Dig       Date:  2018-07-02

9.  EFFECTS OF RENAL DYSFUNCTION ON HEALING OF COLONIC ANASTOMOSIS: EXPERIMENTAL STUDY IN WISTAR RATS.

Authors:  Carlos Eduardo da Silva; João Carlos Domingues Repka; Carlos José Franco de Souza; Jorge Eduardo Fouto Matias
Journal:  Arq Bras Cir Dig       Date:  2018-12-06

10.  IMPLEMENTATION OF ENHANCED RECOVERY AFTER COLORECTAL SURGERY (ERAS) PROTOCOL: INITIAL RESULTS OF THE FIRST BRAZILIAN EXPERIENCE.

Authors:  Uirá Fernandes Teixeira; Paulo Roberto Ott Fontes; Cristiane Weckerle Nazareth Conceição; Carlos Alberto Teixeira Farias; Daieni Fernandes; Ingrid Petroni Ewald; Luciano Vitola; Florentino Fernandes Mendes
Journal:  Arq Bras Cir Dig       Date:  2019-02-07
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