| Literature DB >> 31859038 |
Zahir Ali1, Magdy M Mahfouz1, Shahid Mansoor2.
Abstract
Functional genomics is at the core of studying the exact function of genes. However, homozygous knockouts of essential and pleiotropic effectors (almost 10% of the genome) are not always possible, thus, functions of these genes remain obscured. The tissue-specific genome editing tool (CRISPR-TSKO) recently described by Decaestecker et al., can characterize these indispensable genes and has wide applications in plants.Keywords: CRISPR-Cas9; CRISPR-TSKO; functional genomics; genome editing
Mesh:
Year: 2019 PMID: 31859038 DOI: 10.1016/j.tplants.2019.12.002
Source DB: PubMed Journal: Trends Plant Sci ISSN: 1360-1385 Impact factor: 18.313