Jennifer E Sanner Beauchamp1, Tahani Casameni Montiel2, Chunyan Cai3, Sudha Tallavajhula3, Evelyn Hinojosa4, Munachi N Okpala5, Farhaan S Vahidy5, Sean I Savitz5, Anjail Z Sharrief5. 1. The University of Texas Health Science Center at Houston, Cizik School of Nursing and Institute for Stroke and Cerebrovascular Disease, Houston, Texas. Electronic address: Jennifer.E.Beauchamp@uth.tmc.edu. 2. The University of Texas Health Science Center at Houston, Cizik School of Nursing, Houston, Texas. 3. The University of Texas Health Science Center at Houston, McGovern Medical School, Houston, Texas. 4. The University of Texas Health Science Center at Houston, Institute for Stroke and Cerebrovascular Disease, Houston, Texas. 5. The University of Texas Health Science Center at Houston, Institute for Stroke and Cerebrovascular Disease, McGovern Medical School, Houston, Texas.
Abstract
BACKGROUND AND PURPOSE: Post-stroke anxiety (PSA) is common and disabling. PSA should be considered as an important outcome in stroke. However, there is a lack of understanding of factors that may be linked to PSA. The purpose of this study was to determine the frequency of PSA and sociodemographic and clinical factors associated with PSA in a cohort of racially and ethnically diverse stroke patients. METHODS: We conducted a retrospective study of ischemic and hemorrhagic stroke patients seen in a stroke outpatient clinic from August 1, 2017 to June 30, 2018. Patients were eligible if a Generalized Anxiety Disorder 7-Item (GAD-7) instrument was available. GAD-7 scores greater than or equal to 10 indicated the presence of moderate to severe PSA. Multivariable logistic regression was used to identify independent sociodemographic and clinical factors associated with PSA. RESULTS: Records from 289 stroke patients with a GAD-7 instrument were analyzed. PSA was common (21%; GAD-7 ≥ 10). Fifty-seven percent of females had a GAD-7 greater than or equal to 10 compared to 41% of females who had a GAD-7 less than 10 (P = .03). Multivariable analysis found that self-reported nonmarried status (odds ratio, 3.27; 95% confidence interval, 1.44-7.44), excessive fatigue (odds ratio, 4.46; 95% confidence interval, 1.87-10.63), and depression (odds ratio, 1.24; 95% confidence interval, 1.16-1.33) were independently associated with PSA. CONCLUSIONS: PSA may occur more frequently in those who report non-married, excessive fatigue, or depression. Trials of PSA interventions should consider the potential impact of social support, depression, and comorbid conditions contributing to post-stroke fatigue, including sleep apnea.
BACKGROUND AND PURPOSE: Post-stroke anxiety (PSA) is common and disabling. PSA should be considered as an important outcome in stroke. However, there is a lack of understanding of factors that may be linked to PSA. The purpose of this study was to determine the frequency of PSA and sociodemographic and clinical factors associated with PSA in a cohort of racially and ethnically diverse strokepatients. METHODS: We conducted a retrospective study of ischemic and hemorrhagic strokepatients seen in a strokeoutpatient clinic from August 1, 2017 to June 30, 2018. Patients were eligible if a Generalized Anxiety Disorder 7-Item (GAD-7) instrument was available. GAD-7 scores greater than or equal to 10 indicated the presence of moderate to severe PSA. Multivariable logistic regression was used to identify independent sociodemographic and clinical factors associated with PSA. RESULTS: Records from 289 strokepatients with a GAD-7 instrument were analyzed. PSA was common (21%; GAD-7 ≥ 10). Fifty-seven percent of females had a GAD-7 greater than or equal to 10 compared to 41% of females who had a GAD-7 less than 10 (P = .03). Multivariable analysis found that self-reported nonmarried status (odds ratio, 3.27; 95% confidence interval, 1.44-7.44), excessive fatigue (odds ratio, 4.46; 95% confidence interval, 1.87-10.63), and depression (odds ratio, 1.24; 95% confidence interval, 1.16-1.33) were independently associated with PSA. CONCLUSIONS: PSA may occur more frequently in those who report non-married, excessive fatigue, or depression. Trials of PSA interventions should consider the potential impact of social support, depression, and comorbid conditions contributing to post-stroke fatigue, including sleep apnea.
Authors: Imama Ali Naqvi; Tahani Casameni Montiel; Yazan Bittar; Norma Hunter; Munachi Okpala; Constance Johnson; Mark G Weiner; Sean Savitz; Anjail Sharrief; Jennifer Elizabeth Sanner Beauchamp Journal: JMIR Form Res Date: 2021-03-08