Literature DB >> 31857757

Methods of Treatment and Outcome for Ovarian Germ Cell Tumors.

Assem Ahmed Elbrashy1, Amr Kamal1, Mohamed Ibrahim Fahim1.   

Abstract

Ovarian germ cell tumors account for about 15-20% of all ovarian tumors. They occur mainly in girls, adolescents, and young adults. This study aims to assess the different clinico-pathological factors of ovarian germ cell tumors, treatment methods, and outcome. This is a retrospective observational cohort study including 54 cases with OGCTs which were studied from the period between January 2013 and December 2016. The study was performed at National Cancer Institute (NCI)-Cairo University, Egypt. All cases had cytoreductive surgery in the form of unilateral salpingo-oophorectomy in 42 cases and total abdominal hysterectomy in 12 cases. Complete cytoreduction was achieved in 46 cases while 8 cases had residual disease after surgery. Adjuvant chemotherapy was given in 26 cases (stage II, III, and IV malignant OGCTs). The main treatment of ovarian germ cell tumors is complete cytoreductive surgery which can be achieved in many cases with unilateral salpingo-oophorectomy. Adjuvant chemotherapy is highly recommended in case of malignant ovarian germ cell tumors. © Indian Association of Surgical Oncology 2019.

Entities:  

Keywords:  Cytoreductive surgery (CRS); Germ cell ovarian tumors (GCOT); Management

Year:  2019        PMID: 31857757      PMCID: PMC6895359          DOI: 10.1007/s13193-019-00960-3

Source DB:  PubMed          Journal:  Indian J Surg Oncol        ISSN: 0975-7651


  5 in total

1.  Outcome and prognostic factors in ovarian germ cell malignancies.

Authors:  Chyong-Huey Lai; Ting-Chang Chang; Swei Hsueh; Tzu-I Wu; Angel Chao; Hung-Hsueh Chou; Po-Nan Wang
Journal:  Gynecol Oncol       Date:  2005-03       Impact factor: 5.482

Review 2.  Reproduction beyond cancer: a message of hope for young women.

Authors:  Theodoros Maltaris; Daniel Boehm; Ralf Dittrich; Rudolf Seufert; Heinz Koelbl
Journal:  Gynecol Oncol       Date:  2006-09-25       Impact factor: 5.482

3.  Surveillance after initial surgery for pediatric and adolescent girls with stage I ovarian germ cell tumors: report from the Children's Oncology Group.

Authors:  Deborah F Billmire; John W Cullen; Frederick J Rescorla; Mary Davis; Marc G Schlatter; Thomas A Olson; Marcio H Malogolowkin; Farzana Pashankar; Doojduen Villaluna; Mark Krailo; Rachel A Egler; Carlos Rodriguez-Galindo; A Lindsay Frazier
Journal:  J Clin Oncol       Date:  2014-01-06       Impact factor: 44.544

4.  The role of staging and adjuvant chemotherapy in stage I malignant ovarian germ cell tumors (MOGTs): the MITO-9 study.

Authors:  G Mangili; C Sigismondi; D Lorusso; G Cormio; M Candiani; G Scarfone; F Mascilini; A Gadducci; A M Mosconi; P Scollo; C Cassani; S Pignata; G Ferrandina
Journal:  Ann Oncol       Date:  2017-02-01       Impact factor: 32.976

5.  Reproductive and sexual function after platinum-based chemotherapy in long-term ovarian germ cell tumor survivors: a Gynecologic Oncology Group Study.

Authors:  David M Gershenson; Anna M Miller; Victoria L Champion; Patrick O Monahan; Qianqian Zhao; David Cella; Stephen D Williams
Journal:  J Clin Oncol       Date:  2007-07-01       Impact factor: 44.544

  5 in total
  2 in total

Review 1.  cAMP Signaling in Cancer: A PKA-CREB and EPAC-Centric Approach.

Authors:  Muhammad Bilal Ahmed; Abdullah A A Alghamdi; Salman Ul Islam; Joon-Seok Lee; Young-Sup Lee
Journal:  Cells       Date:  2022-06-24       Impact factor: 7.666

2.  Germinal ovarian tumors in reproductive age women: Fertility-sparing and outcome.

Authors:  Miriam Dellino; Erica Silvestris; Vera Loizzi; Angelo Paradiso; Rosalia Loiacono; Carla Minoia; Antonella Daniele; Gennaro Cormio
Journal:  Medicine (Baltimore)       Date:  2020-09-25       Impact factor: 1.817

  2 in total

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