Literature DB >> 31857549

Gamma Knife Radiosurgical Pallidotomy for Dystonia: Not a Fallen Angel.

Manjul Tripathi1, Srinivasan Sharan2, Sahil Mehta3, Harsh Deora4, Nishant S Yagnick1, Narendra Kumar5, Chirag K Ahuja6, Aman Batish1, Jenil Gurnani1.   

Abstract

The authors report a case of successful management of right side hemidystonia with gamma knife radiosurgery. A 24-year-old male with a history of birth asphyxia subsequently developed worsening right-sided torsional hemidystonia which failed to respond to the medical management. MRI of the brain was unremarkable. Stereotactic gamma knife radiosurgery (GKRS) was performed to create a lesion in the left posteroventral globus pallidum. The patient gradually improved over a course of 18 months without any complication. He obtained 61% improvement in dystonia rating scale. Radiosurgical pallidotomy is often viewed with suspicion and functional neurosurgeons show reluctance in preferring it to stereotactic radio frequency lesioning or stimulation surgery. The authors would like to highlight the chances of not only control, but also cure of the disease with this cost-effective treatment modality.

Entities:  

Keywords:  Dystonia; Gamma-knife; pallidotomy; stereotactic radiosurgery

Mesh:

Year:  2019        PMID: 31857549     DOI: 10.4103/0028-3886.273644

Source DB:  PubMed          Journal:  Neurol India        ISSN: 0028-3886            Impact factor:   2.117


  2 in total

1.  Is Glutamine Responsible for the Radiosensitivity of Subthalamic Nucleus?

Authors:  Manjul Tripathi; Sonikpreet Aulakh
Journal:  Stereotact Funct Neurosurg       Date:  2020-11-23       Impact factor: 1.875

2.  Safety and efficacy of unilateral and bilateral pallidotomy for primary dystonia.

Authors:  Shiro Horisawa; Atsushi Fukui; Nobuhiko Takeda; Takakazu Kawamata; Takaomi Taira
Journal:  Ann Clin Transl Neurol       Date:  2021-03-15       Impact factor: 4.511

  2 in total

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