Literature DB >> 31857364

Activated protein C anticoagulant activity is enhanced by skeletal muscle myosin.

Mary J Heeb1, José A Fernández2, Atsuki Yamashita2, Olivia R McDowell2, Zihan Guo2, Laurent O Mosnier2, Hiroshi Deguchi2, John H Griffin1.   

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Year:  2019        PMID: 31857364      PMCID: PMC7395292          DOI: 10.3324/haematol.2019.242982

Source DB:  PubMed          Journal:  Haematologica        ISSN: 0390-6078            Impact factor:   9.941


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10.  Effects of protein S and factor Xa on peptide bond cleavages during inactivation of factor Va and factor VaR506Q by activated protein C.

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1.  Plasma skeletal muscle myosin phenotypes identified by immunoblotting are associated with pulmonary embolism occurrence in young adults.

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3.  Procoagulant activities of skeletal muscle and cardiac myosins require both myosin protein and myosin-associated anionic phospholipids.

Authors:  Shravan Morla; Hiroshi Deguchi; José A Fernández; Wolfram Ruf; Rolf A Brekken; John H Griffin
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4.  Skeletal muscle myosin and cardiac myosin attenuate heparin's antithrombin-dependent anticoagulant activity.

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