Literature DB >> 31855780

Lanostane triterpenoids from cultivated fruiting bodies of the wood-rot basidiomycete Ganoderma casuarinicola.

Masahiko Isaka1, Panida Chinthanom2, Pranee Rachtawee2, Wilunda Choowong2, Rattaket Choeyklin2, Tuksaporn Thummarukcharoen2.   

Abstract

Sixteen previously undescribed lanostane-type triterpenoids (1-16), together with fourteen known compounds, were isolated from cultivated fruiting bodies of the basidiomycete Ganoderma casuarinicola, a recently described species. The structures were elucidated on the basis of NMR spectroscopic and mass spectrometry data. Two of these compounds, 9 and 10, showed antimalarial activity with IC50 values of 9.7 and 9.2 μg/ml, respectively.
Copyright © 2019 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Antimalarial activity; Ganoderma casuarinicola; Ganodermataceae; Lanostane

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Year:  2019        PMID: 31855780     DOI: 10.1016/j.phytochem.2019.112225

Source DB:  PubMed          Journal:  Phytochemistry        ISSN: 0031-9422            Impact factor:   4.072


  1 in total

Review 1.  Bioactive small secondary metabolites from the mushrooms Lentinula edodes and Flammulina velutipes.

Authors:  Emi Fukushima-Sakuno
Journal:  J Antibiot (Tokyo)       Date:  2020-07-30       Impact factor: 2.649

  1 in total

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