Visible-Light-Induced para-Selective C(sp2)-H Difluoroalkylation of Diverse (Hetero)aromatic Carbonyls.

An efficient visible-light-induced para-selective C(sp2)-H difluoroalkylation of diverse electron-deficient (hetero)aromatic carbonyls (aldehydes and ketones) at ambient temperature has been developed by employing Ir(ppy)3 as the catalyst and 1,10-phenanthroline as the additive. This protocol was highlighted by its wide substrate scope, high regioselectivity, low catalyst usage, and operational simplicity.