| Literature DB >> 31851180 |
Abstract
Platelets are an easily accessible model for the study of biochemical mechanisms of mental diseases, including schizophrenia and depression. This literature review addresses a role of platelet activation in the pathogenesis of mental diseases. Platelet activation observed in patients with schizophrenia, depression and other mental illnesses is associated with the development of cardiovascular disease and an increased risk of thrombotic complications, which can be the main cause of morbidity and mortality in patients with mental disorders. A deeper understanding of the biochemical mechanisms of mental disorders will help in the study of clinical consequences of these disorders and in choosing the right therapeutic strategy for patients.Entities:
Keywords: coagulation; fibrinolysis; hemostasis; mental disorders; platelets
Mesh:
Year: 2019 PMID: 31851180 DOI: 10.17116/jnevro2019119111103
Source DB: PubMed Journal: Zh Nevrol Psikhiatr Im S S Korsakova ISSN: 1997-7298