Henry Chubb1, Scott R Ceresnak2, Kara S Motonaga2, Anne M Dubin2. 1. Division of Pediatric Cardiology, Department of Pediatrics, Stanford University, Palo Alto, CA, USA; Department of Cardiothoracic Surgery, Stanford University School of Medicine, 780 Welch Road, Stanford, CA 9430, USA. Electronic address: mhchubb@stanford.edu. 2. Division of Pediatric Cardiology, Department of Pediatrics, Stanford University, Palo Alto, CA, USA.
Abstract
BACKGROUND: There are currently no published algorithms for calculation of age-dependent QRS duration z-scores. The absence of a standardized measure has limited researchers' abilities to compare ECG measurements of electrical synchrony between subjects of different ages or longitudinally over time. METHODS: Four existing studies of normal ECG measurements (total 19,062 subjects) were used to estimate age and sex-dependent means and standard deviations. RESULTS: Weighted means and standard deviations were best estimated by cubic functions to create z-score algorithms. CONCLUSION: Nomograms and algorithms for QRS duration z-scores may be estimated to compare ECG findings in both children and adults.
BACKGROUND: There are currently no published algorithms for calculation of age-dependent QRS duration z-scores. The absence of a standardized measure has limited researchers' abilities to compare ECG measurements of electrical synchrony between subjects of different ages or longitudinally over time. METHODS: Four existing studies of normal ECG measurements (total 19,062 subjects) were used to estimate age and sex-dependent means and standard deviations. RESULTS: Weighted means and standard deviations were best estimated by cubic functions to create z-score algorithms. CONCLUSION: Nomograms and algorithms for QRS duration z-scores may be estimated to compare ECG findings in both children and adults.
Authors: Aenne S von Falkenhausen; Rebecca Freudling; Melanie Waldenberger; Christian Gieger; Annette Peters; Martina Müller-Nurasyid; Stefan Kääb; Moritz F Sinner Journal: Aging (Albany NY) Date: 2022-07-05 Impact factor: 5.955