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Literature DB >> 31846618

The role of liposomes in clinical nanomedicine development. What now? Now what?

Daan J A Crommelin¹, Peter van Hoogevest², Gert Storm³.

Abstract

The rapid rise in interest in 'nanomedicines' in the academic world over the last twenty years and the claims of success led to calls for reflection. The main body of text of this Commentary will be on answering the question: 'where to go with nanomedicines'? Research priorities for the future will be outlined based on experience with the most successful nanomedicines family within the broad field of nanomedicine so far: liposomes. An analysis of currently clinically tested, approved and marketed liposome-drug combinations provides these insights.

Keywords: Clinical trials; Liposomes; Nanomedicines

Mesh：

Substances：
Liposomes

Year: 2019 PMID： 31846618 DOI： 10.1016/j.jconrel.2019.12.023

Source DB: PubMed Journal: J Control Release ISSN： 0168-3659 Impact factor: 9.776

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Cited

38 in total

1. Design, fabrication and applications of tetrahedral DNA nanostructure-based multifunctional complexes in drug delivery and biomedical treatment.

Authors: Tao Zhang; Taoran Tian; Ronghui Zhou; Songhang Li; Wenjuan Ma; Yuxin Zhang; Nanxin Liu; Sirong Shi; Qianshun Li; Xueping Xie; Yichen Ge; Mengting Liu; Qi Zhang; Shiyu Lin; Xiaoxiao Cai; Yunfeng Lin
Journal: Nat Protoc Date: 2020-07-15 Impact factor: 13.491

2. Endogenous Oleoylethanolamide Crystals Loaded Lipid Nanoparticles with Enhanced Hydrophobic Drug Loading Capacity for Efficient Stroke Therapy.

Authors: Shichao Wu; Di Liao; Xi Li; Zeyu Liu; Lin Zhang; Fong Ming Mo; Shuo Hu; Jian Xia; Xiangrui Yang
Journal: Int J Nanomedicine Date: 2021-12-21

3. Reactive Oxygen Species (ROS) Activated Liposomal Cell Delivery using a Boronate-Caged Guanidine Lipid.

Authors: Jinchao Lou; Megan L Qualls; Macy M Hudson; Dillon P McBee; Joshua A Baccile; Michael D Best
Journal: Chemistry Date: 2022-06-27 Impact factor: 5.020

4. Platelet-mimicking procoagulant nanoparticles augment hemostasis in animal models of bleeding.

Authors: Ujjal Didar Singh Sekhon; Kelsey Swingle; Aditya Girish; Norman Luc; Maria de la Fuente; Jurgis Alvikas; Shannon Haldeman; Adnan Hassoune; Kaisal Shah; Youjoung Kim; Steven Eppell; Jeffrey Capadona; Andrew Shoffstall; Matthew D Neal; Wei Li; Marvin Nieman; Anirban Sen Gupta
Journal: Sci Transl Med Date: 2022-01-26 Impact factor: 19.319

Review 5. Challenges and opportunities in metastatic breast cancer treatments: Nano-drug combinations delivered preferentially to metastatic cells may enhance therapeutic response.

Authors: Jesse Yu; Qingxin Mu; Millie Fung; Xiaolin Xu; Linxi Zhu; Rodney J Y Ho
Journal: Pharmacol Ther Date: 2022-01-06 Impact factor: 13.400

6. Synergistic Antitumor Efficacy Mediated by Liposomal Co-Delivery of Polymeric Micelles of Vinorelbine and Cisplatin in Non-Small Cell Lung Cancer.

Authors: Shuhang Wang; Jingxin Gou; Yue Wang; Xinyi Tan; Linxuan Zhao; Xiangqun Jin; Xing Tang
Journal: Int J Nanomedicine Date: 2021-03-22

The role of liposomes in clinical nanomedicine development. What now? Now what?

1. Design, fabrication and applications of tetrahedral DNA nanostructure-based multifunctional complexes in drug delivery and biomedical treatment.

2. Endogenous Oleoylethanolamide Crystals Loaded Lipid Nanoparticles with Enhanced Hydrophobic Drug Loading Capacity for Efficient Stroke Therapy.

3. Reactive Oxygen Species (ROS) Activated Liposomal Cell Delivery using a Boronate-Caged Guanidine Lipid.

4. Platelet-mimicking procoagulant nanoparticles augment hemostasis in animal models of bleeding.

Review 5. Challenges and opportunities in metastatic breast cancer treatments: Nano-drug combinations delivered preferentially to metastatic cells may enhance therapeutic response.

6. Synergistic Antitumor Efficacy Mediated by Liposomal Co-Delivery of Polymeric Micelles of Vinorelbine and Cisplatin in Non-Small Cell Lung Cancer.

Review 7. Cationic Nanoparticle-Based Cancer Vaccines.

Review 8. Nanomedicines in the treatment of colon cancer: a focus on metallodrugs.

Review 9. Peptide-Enabled Targeted Delivery Systems for Therapeutic Applications.

Review 10. Recent Advances in Stimulus-Responsive Nanocarriers for Gene Therapy.