Jürgen Harreiter1, Gernot Desoye2, Mireille N M van Poppel3, Alexandra Kautzky-Willer1, Fidelma Dunne4, Rosa Corcoy5,6,7, Roland Devlieger8, David Simmons9,10, Juan M Adelantado, Peter Damm, Elizabeth Reinhardt Mathiesen, Dorte Moeller Jensen, Lise Lotte T Anderson, Annunziata Lapolla, Maria G Dalfrà, Alessandra Bertolotto, Ewa Wender-Ozegowska, Agnieszka Zawiejska, David J Hill, Frank J Snoek. 1. Gender Medicine Unit, Division of Endocrinology and Metabolism, Department of Medicine III, Medical University of Vienna, Vienna, Austria. 2. Department of Obstetrics and Gynecology, Medical University of Graz, Graz, Austria. 3. Institute of Sport Science, University of Graz, Graz, Austria. 4. National University of Ireland, Galway, Ireland. 5. Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau, Barcelona, Spain. 6. CIBER Bioengineering, Biomaterials and Nanotechnology, Instituto de Salud Carlos III, Madrid, Spain. 7. Departament de Medicina, Universitat Autònoma de Barcelona, Bellaterra, Spain. 8. KU Leuven Department of Development and Regeneration: Pregnancy, Fetus and Neonate, Gynaecology and Obstetrics, University Hospitals Leuven, Leuven, Belgium. 9. Institute of Metabolic Science, Addenbrookes Hospital, Cambridge, England. da.simmons@westernsydney.edu.au. 10. School of Medicine, Macarthur Clinical School, Western Sydney University, Locked Bag 1797, Campbelltown, NSW, 2751, Australia. da.simmons@westernsydney.edu.au.
Abstract
PURPOSE OF REVIEW: The DALI (vitamin D and lifestyle intervention in the prevention of gestational diabetes mellitus (GDM)) study aimed to prevent GDM with lifestyle interventions or Vitamin D supplementation (1600 IU/day). This review summarizes the learnings from the DALI studies among pregnant women with a BMI ≥ 29 kg/m2. RECENT FINDINGS: Women diagnosed with GDM earlier in pregnancy had a worse metabolic profile than those diagnosed later. A combined physical activity (PA) and healthy eating (HE) lifestyle intervention improved both behaviours, limited gestational weight gain (GWG) and was cost-effective. Although GDM risk was unchanged, neonatal adiposity was reduced due to less sedentary time. Neither PA nor HE alone limited GWG or GDM risk. Fasting glucose was higher with HE only intervention, and lower with Vitamin D supplementation. Our combined intervention did not prevent GDM, but was cost-effective, limited GWG and reduced neonatal adiposity.
PURPOSE OF REVIEW: The DALI (vitamin D and lifestyle intervention in the prevention of gestational diabetes mellitus (GDM)) study aimed to prevent GDM with lifestyle interventions or Vitamin D supplementation (1600 IU/day). This review summarizes the learnings from the DALI studies among pregnant women with a BMI ≥ 29 kg/m2. RECENT FINDINGS:Women diagnosed with GDM earlier in pregnancy had a worse metabolic profile than those diagnosed later. A combined physical activity (PA) and healthy eating (HE) lifestyle intervention improved both behaviours, limited gestational weight gain (GWG) and was cost-effective. Although GDM risk was unchanged, neonatal adiposity was reduced due to less sedentary time. Neither PA nor HE alone limited GWG or GDM risk. Fasting glucose was higher with HE only intervention, and lower with Vitamin D supplementation. Our combined intervention did not prevent GDM, but was cost-effective, limited GWG and reduced neonatal adiposity.
Authors: Camille E Powe; Catherine Allard; Marie-Claude Battista; Myriam Doyon; Luigi Bouchard; Jeffrey L Ecker; Patrice Perron; Jose C Florez; Ravi Thadhani; Marie-France Hivert Journal: Diabetes Care Date: 2016-05-13 Impact factor: 19.112
Authors: Judith G M Jelsma; Mireille N M van Poppel; Sander Galjaard; Gernot Desoye; Rosa Corcoy; Roland Devlieger; Andre van Assche; Dirk Timmerman; Goele Jans; Jurgen Harreiter; Alexandra Kautzky-Willer; Peter Damm; Elisabeth R Mathiesen; Dorte M Jensen; Liselotte Andersen; Fidelma Dunne; Annunziata Lapolla; Graziano Di Cianni; Alessandra Bertolotto; Ewa Wender-Oegowska; Agnieszka Zawiejska; Kinga Blumska; David Hill; Pablo Rebollo; Frank J Snoek; David Simmons Journal: BMC Pregnancy Childbirth Date: 2013-07-05 Impact factor: 3.007
Authors: Linda de Wit; Judith G M Jelsma; Mireille N M van Poppel; Annick Bogaerts; David Simmons; Gernot Desoye; Rosa Corcoy; Alexandra Kautzky-Willer; Jürgen Harreiter; Andre van Assche; Roland Devlieger; Dirk Timmerman; David Hill; Peter Damm; Elisabeth R Mathiesen; Ewa Wender-Ozegowska; Agnieszka Zawiejska; Pablo Rebollo; Annunziata Lapolla; Maria G Dalfrà; Stefano Del Prato; Alessandra Bertolotto; Fidelma Dunne; Dorte M Jensen; Liselotte Andersen; Frank J Snoek Journal: BMC Pregnancy Childbirth Date: 2015-07-31 Impact factor: 3.007
Authors: Karen Broekhuizen; David Simmons; Roland Devlieger; André van Assche; Goele Jans; Sander Galjaard; Rosa Corcoy; Juan M Adelantado; Fidelma Dunne; Gernot Desoye; Jürgen Harreiter; Alexandra Kautzky-Willer; Peter Damm; Elisabeth R Mathiesen; Dorte M Jensen; Liselotte L Andersen; Annunziata Lapolla; Maria G Dalfra; Alessandra Bertolotto; Ewa Wender-Ozegowska; Agnieszka Zawiejska; David Hill; Frank J Snoek; Judith G M Jelsma; Judith E Bosmans; Mireille N M van Poppel; Johanna M van Dongen Journal: Int J Behav Nutr Phys Act Date: 2018-03-14 Impact factor: 6.457
Authors: Aleksandra S Tkachuk; Elena A Vasukova; Anna D Anopova; Tatiana L Karonova; Evgenii A Pustozerov; Yana A Teplova; Angelina I Eriskovskaya; Artem O Isakov; Elena Y Vasilieva; Maria A Kokina; Irina Y Zazerskaya; Tatiana M Pervunina; Elena N Grineva; Polina V Popova Journal: Nutrients Date: 2022-05-22 Impact factor: 6.706
Authors: Anja Elaine Sørensen; Mireille N M van Poppel; Gernot Desoye; Peter Damm; David Simmons; Dorte Møller Jensen; Louise Torp Dalgaard Journal: Cells Date: 2021-01-15 Impact factor: 6.600
Authors: Cezary Wojtyla; Pawel Stanirowski; Pawel Gutaj; Michal Ciebiera; Andrzej Wojtyla Journal: Int J Environ Res Public Health Date: 2021-01-11 Impact factor: 3.390